Volume 9 (2023) – 49 articles

Cover Picture: Updated soon.

Editorial

Current landscape and future directions for systemic treatments of hepatocellular carcinoma

Leonardo G. Fonseca, Flair J. Carrilho

This article belongs to the Special Issue Systemic Treatment for Hepatocellular Carcinoma

Hepatoma Res 2023;9:27. DOI: 10.20517/2394-5079.2023.63

Editorial | Published on: 20 Jun 2023

Improve the precise pathological diagnosis of intrahepatic cholangiocarcinoma: introduction to 2022 expert consensus on pathological diagnosis of intrahepatic cholangiocarcinoma in China

Xin Zhang, ... Ji Yuan

This article belongs to the Special Issue Challenges and Opportunities for Treating Intrahepatic Cholangiocarcinoma

Hepatoma Res 2023;9:5. DOI: 10.20517/2394-5079.2023.11

Editorial | Published on: 8 Mar 2023

Review

Targeted mutation-based therapy for intrahepatic cholangiocarcinoma

Facai Yang, ... Bin Yi

This article belongs to the Special Issue Challenges and Opportunities for Treating Intrahepatic Cholangiocarcinoma

Hepatoma Res 2023;9:48. DOI: 10.20517/2394-5079.2023.68

Review | Published on: 15 Nov 2023

The tumor microenvironment in hepatocarcinoma: dissecting the functions of cancer-associated fibroblasts

Massimiliano Cadamuro, ... Luca Fabris

This article belongs to the Special Issue Liver Transplantation for Hepatocellular Carcinoma: Up to Date

Hepatoma Res 2023;9:47. DOI: 10.20517/2394-5079.2023.94

Review | Published on: 5 Nov 2023

The role of exosomes in therapeutic resistance of hepatocellular carcinoma

Jin Wang, ... Xia Wang

This article belongs to the Special Issue Hepatocellular Carcinoma and Therapeutic Resistance

Hepatoma Res 2023;9:46. DOI: 10.20517/2394-5079.2023.85

Review | Published on: 29 Oct 2023

Treatment of intrahepatic cholangiocarcinoma: evidence for the role of percutaneous ablation

Reto Bale, Timothy M. Pawlik

This article belongs to the Special Issue Challenges and Opportunities for Treating Intrahepatic Cholangiocarcinoma

Hepatoma Res 2023;9:44. DOI: 10.20517/2394-5079.2023.71

Review | Published on: 23 Oct 2023

Trans-arterial chemoembolization and radioembolization for treatment of intrahepatic cholangiocarcinoma

Thomas An, Eric Wehrenberg-Klee

This article belongs to the Special Issue Challenges and Opportunities for Treating Intrahepatic Cholangiocarcinoma

Hepatoma Res 2023;9:43. DOI: 10.20517/2394-5079.2023.60

Review | Published on: 12 Oct 2023

Strategy for ERCP stenting in cholangiocarcinoma

Radovan Prijic, ... Pave Markos

This article belongs to the Special Issue Endoscopy for Liver Cancer and Related Complications

Hepatoma Res 2023;9:42. DOI: 10.20517/2394-5079.2023.20

Review | Published on: 25 Sep 2023

Angiogenesis: the Yin and Yang in intrahepatic cholangiocarcinoma

Adriana Romanzi, Erica Villa

This article belongs to the Special Issue Molecular Pathogenesis and Drivers of Cholangiocarcinoma

Hepatoma Res 2023;9:41. DOI: 10.20517/2394-5079.2023.53

Review | Published on: 22 Aug 2023

Advanced and emerging radiation therapy approaches for intrahepatic cholangiocarcinoma

Kanokphorn Thonglert, ... Smith Apisarnthanarax

This article belongs to the Special Issue Challenges and Opportunities for Treating Intrahepatic Cholangiocarcinoma

Hepatoma Res 2023;9:40. DOI: 10.20517/2394-5079.2023.47

Review | Published on: 17 Aug 2023

The role of gut microbiome and fecal microbiota transplantation in liver cancer and related complications: mechanisms and therapeutic potentials

Min Dai, ... Louis H. S. Lau

This article belongs to the Special Issue Endoscopy for Liver Cancer and Related Complications

Hepatoma Res 2023;9:39. DOI: 10.20517/2394-5079.2023.33

Review | Published on: 9 Aug 2023

Review of IDH mutations and potential therapies for intrahepatic cholangiocarcinoma

Samantha M. Ruff, Mary Dillhoff

This article belongs to the Special Issue Challenges and Opportunities for Treating Intrahepatic Cholangiocarcinoma

Hepatoma Res 2023;9:37. DOI: 10.20517/2394-5079.2023.51

Review | Published on: 2 Aug 2023

Insights on liver transplantation and multimodal treatment for intrahepatic cholangiocarcinoma

Shankar Logarajah, ... Lavanya Yohanathan

This article belongs to the Special Issue Advances in Surgical and Multimodality Treatment for (of) Cholangiocarcinoma

Hepatoma Res 2023;9:36. DOI: 10.20517/2394-5079.2023.02

Review | Published on: 30 Jul 2023

Liver transplantation for intrahepatic cholangiocarcinoma: a narrative review of the latest advances

Francisco Calderon Novoa, ... Martin de Santibañes

This article belongs to the Special Issue Challenges and Opportunities for Treating Intrahepatic Cholangiocarcinoma

Hepatoma Res 2023;9:33. DOI: 10.20517/2394-5079.2023.36

Review | Published on: 27 Jul 2023

Genomic alterations in intrahepatic cholangiocarcinoma

Sara E. Young, ... Daniela Sia

This article belongs to the Special Issue Molecular Pathogenesis and Drivers of Cholangiocarcinoma

Hepatoma Res 2023;9:34. DOI: 10.20517/2394-5079.2023.37

Review | Published on: 27 Jul 2023

Tumor microenvironment highlighting tumor-associated macrophages and immune cells

Giulio Lodetti Zangrandi, ... Chiara Raggi

This article belongs to the Special Issue Molecular Pathogenesis and Drivers of Cholangiocarcinoma

Hepatoma Res 2023;9:32. DOI: 10.20517/2394-5079.2023.32

Review | Published on: 27 Jul 2023

Neoadjuvant chemotherapy alone or combined with trans-arterial therapies for downstaging unresectable intrahepatic cholangiocarcinoma to surgical resection: a narrative review

Francesca Caputo, ... Matteo Cescon

This article belongs to the Special Issue Advances in Surgical and Multimodality Treatment for (of) Cholangiocarcinoma

Hepatoma Res 2023;9:31. DOI: 10.20517/2394-5079.2022.71

Review | Published on: 19 Jul 2023

Cholangiocarcinoma tumor microenvironment highlighting fibrosis and matrix components

Alessandra Caligiuri, ... Alessandra Gentilini

This article belongs to the Special Issue Molecular Pathogenesis and Drivers of Cholangiocarcinoma

Hepatoma Res 2023;9:30. DOI: 10.20517/2394-5079.2023.23

Review | Published on: 12 Jul 2023

The future direction of liver transplantation for intrahepatic cholangiocarcinoma

Miho Akabane, ... Kazunari Sasaki

This article belongs to the Special Issue Challenges and Opportunities for Treating Intrahepatic Cholangiocarcinoma

Hepatoma Res 2023;9:29. DOI: 10.20517/2394-5079.2023.45

Review | Published on: 6 Jul 2023

Role of diagnostic radiology in the management of intrahepatic cholangiocarcinoma

Shadi Afyouni, ... Ihab R. Kamel

This article belongs to the Special Issue Challenges and Opportunities for Treating Intrahepatic Cholangiocarcinoma

Hepatoma Res 2023;9:28. DOI: 10.20517/2394-5079.2023.29

Review | Published on: 24 Jun 2023

Genomic alterations and targeted therapies in extrahepatic cholangiocarcinoma

Arnau Oronich, ... Robert Montal

This article belongs to the Special Issue Molecular Pathogenesis and Drivers of Cholangiocarcinoma

Hepatoma Res 2023;9:26. DOI: 10.20517/2394-5079.2023.04

Review | Published on: 18 Jun 2023

Mitochondrial calcium signaling in cholangiocarcinoma

Ana Carolina Loyola-Machado, ... Michael H. Nathanson

This article belongs to the Special Issue Molecular Pathogenesis and Drivers of Cholangiocarcinoma

Hepatoma Res 2023;9:25. DOI: 10.20517/2394-5079.2023.28

Review | Published on: 12 Jun 2023

The impact of lymphadenectomy on intrahepatic cholangiocarcinoma management and prognosis: a comprehensive review

Paschalis Gavriilidis, ... Timothy M. Pawlik

This article belongs to the Special Issue Challenges and Opportunities for Treating Intrahepatic Cholangiocarcinoma

Hepatoma Res 2023;9:24. DOI: 10.20517/2394-5079.2023.26

Review | Published on: 11 Jun 2023

MRI for screening and surveillance for hepatocellular cancer in NAFLD and NASH

Christine Pocha, Sabina Choudhry

This article belongs to the Special Issue Surveillance in Patients with Nonalcoholic Steatohepatitis-related Hepatocellular Carcinoma

Hepatoma Res 2023;9:22. DOI: 10.20517/2394-5079.2023.08

Review | Published on: 31 May 2023

Biomarkers for living donor liver transplants in hepatocellular carcinoma

Edward Butt, ... Moghe Akshata

This article belongs to the Special Issue The Role of Living Donor Liver Transplantation in the Treatment of Hepatocellular Carcinoma and Cholangiocarcinoma

Hepatoma Res 2023;9:20. DOI: 10.20517/2394-5079.2023.25

Review | Published on: 21 May 2023

Expression and function of collagens in intrahepatic cholangiocarcinoma

Tania Colasanti, ... Carmine Mancone

This article belongs to the Special Issue Molecular Pathogenesis and Drivers of Cholangiocarcinoma

Hepatoma Res 2023;9:19. DOI: 10.20517/2394-5079.2022.94

Review | Published on: 18 May 2023

Imaging after liver-directed therapy: evidenced-based update of the LI-RADS treatment response algorithm

Marisa Martin, ... Mishal Mendiratta-Lala

This article belongs to the Special Issue Interventional Radiology in Treatment of Hepatocellular Carcinoma

Hepatoma Res 2023;9:21. DOI: 10.20517/2394-5079.2022.95

Review | Published on: 16 May 2023

Surgical management of intrahepatic cholangiocarcinoma

Samantha M. Ruff, Timothy M. Pawlik

This article belongs to the Special Issue Challenges and Opportunities for Treating Intrahepatic Cholangiocarcinoma

Hepatoma Res 2023;9:17. DOI: 10.20517/2394-5079.2023.18

Review | Published on: 14 May 2023

Combined hepatocellular-cholangiocarcinoma: morpho-molecular updates and considerations

Naghia Ahmed, ... Federica Pedica

This article belongs to the Special Issue Liver Tumors of Unidentified Primary: are All HCC or HCC-CCA?

Hepatoma Res 2023;9:16. DOI: 10.20517/2394-5079.2022.81

Review | Published on: 27 Apr 2023

Signaling and molecular networks related to development and inflammation involved in CCA initiation and progression

Antonio Cigliano, ... Massimiliano Cadamuro

This article belongs to the Special Issue Molecular Pathogenesis and Drivers of Cholangiocarcinoma

Hepatoma Res 2023;9:15. DOI: 10.20517/2394-5079.2023.09

Review | Published on: 23 Apr 2023

Chemoembolization with Degradable Starch Microspheres (DSM-TACE): expanding indications in HCC multidisciplinary tumor board

Umberto Rozzanigo, ... Alberto Brolese

This article belongs to the Special Issue Interventional Radiology in Treatment of Hepatocellular Carcinoma

Hepatoma Res 2023;9:14. DOI: 10.20517/2394-5079.2022.66

Review | Published on: 20 Apr 2023

Surgery for hepatocellular carcinoma and intrahepatic cholangiocarcinoma: milestone changes in the last two decades potentially affecting current guidelines

Federica Cipriani, ... Luca Aldrighetti

This article belongs to the Special Issue Liver Tumors of Unidentified Primary: are All HCC or HCC-CCA?

Hepatoma Res 2023;9:13. DOI: 10.20517/2394-5079.2022.80

Review | Published on: 19 Apr 2023

Ultrasonography in surveillance for hepatocellular carcinoma in patients with non-alcoholic fatty liver disease

Theresa J. Hydes, ... Timothy J. Cross

This article belongs to the Special Issue Surveillance in Patients with Nonalcoholic Steatohepatitis-related Hepatocellular Carcinoma

Hepatoma Res 2023;9:12. DOI: 10.20517/2394-5079.2022.97

Review | Published on: 30 Mar 2023

Challenges and barriers in hepatocellular carcinoma (HCC) surveillance for patients with non-alcoholic fatty liver disease (NAFLD)

Kara Wegermann, ... Cynthia A. Moylan

This article belongs to the Special Issue Surveillance in Patients with Nonalcoholic Steatohepatitis-related Hepatocellular Carcinoma

Hepatoma Res 2023;9:11. DOI: 10.20517/2394-5079.2022.92

Review | Published on: 30 Mar 2023

The role of tumor microenvironment in cholangiocarcinoma

Maria Eva Argenziano, ... Luca Maroni

This article belongs to the Special Issue Molecular Pathogenesis and Drivers of Cholangiocarcinoma

Hepatoma Res 2023;9:9. DOI: 10.20517/2394-5079.2022.98

Review | Published on: 23 Mar 2023

Contrast-enhanced ultrasound for hepatocellular carcinoma detection and diagnosis in the context of nonalcoholic fatty liver disease

Kevin G. King, ... David S. Lu

This article belongs to the Special Issue Surveillance in Patients with Nonalcoholic Steatohepatitis-related Hepatocellular Carcinoma

Hepatoma Res 2023;9:8. DOI: 10.20517/2394-5079.2022.49

Review | Published on: 20 Mar 2023

Issue on combined locoregional and systemic treatment for hepatocellular carcinoma

Yi-Chia (Jasmine) Wu, ... Nikolaos Pyrsopoulos

This article belongs to the Special Issue Systemic Treatment for Hepatocellular Carcinoma

Hepatoma Res 2023;9:6. DOI: 10.20517/2394-5079.2022.37

Review | Published on: 15 Mar 2023

Hepatocellular carcinoma after treatment of hepatitis C with direct-acting antivirals: a critical re-appraisal

Elias Kouroumalis, ... Argyro Voumvouraki

Hepatoma Res 2023;9:4. DOI: 10.20517/2394-5079.2022.35

Review | Published on: 15 Feb 2023

Targeting the interactions between lymphocytes and liver cancer stem cells in combination with immunotherapy is a promising therapeutic strategy

Wo-Ming Chen, ... Lei Li

This article belongs to the Special Issue Hepatocellular Carcinoma and Therapeutic Resistance

Hepatoma Res 2023;9:2. DOI: 10.20517/2394-5079.2022.52

Review | Published on: 13 Feb 2023

Assessment of response to liver directed radiation-based therapies: Current guidelines, challenges, and future directions

Anisha Banda, ... Guilherme Moura Cunha

This article belongs to the Special Issue Interventional Radiology in Treatment of Hepatocellular Carcinoma

Hepatoma Res 2023;9:1. DOI: 10.20517/2394-5079.2022.60

Review | Published on: 8 Jan 2023

Original Article

Barriers to surveillance for hepatocellular cancer among patients with chronic liver disease -providers’ perspectives

Eliza W. Beal, ... Allan Tsung

This article belongs to the Special Issue Advances in Surveillance of HCC in Patients with Cirrhosis

Hepatoma Res 2023;9:45. DOI: 10.20517/2394-5079.2023.75

Original Article | Published on: 29 Oct 2023

The role of liver transplant for intrahepatic cholangiocarcinoma: the UK NHSBT liver advisory group pilot programme

Abdul Rahman Hakeem, ... on behalf of the NHS Blood and Transplant Liver Transplantation for Cholangiocarcinoma Fixed Term Working Group†

This article belongs to the Special Issue Challenges and Opportunities for Treating Intrahepatic Cholangiocarcinoma

Hepatoma Res 2023;9:38. DOI: 10.20517/2394-5079.2023.59

Original Article | Published on: 7 Aug 2023

Hepatocellular carcinoma in Pacific Islanders: comparison of Pacific Island-born vs. US-born

Shelby K. Yee, ... Linda L. Wong

This article belongs to the Special Issue Racial/Ethnic Differences in Liver Cancer

Hepatoma Res 2023;9:7. DOI: 10.20517/2394-5079.2022.85

Original Article | Published on: 16 Mar 2023

Risk of hepatocellular carcinoma development in long-term nucles(t)ide analog suppressed patients with chronic hepatitis B

Massimo Fasano, ... Teresa Antonia Santantonio

Hepatoma Res 2023;9:3. DOI: 10.20517/2394-5079.2022.51

Original Article | Published on: 16 Feb 2023

Systematic Review

Hepatic venous pressure gradient in hepatic resection for hepatocellular carcinoma

Sarah Shalaby, ... Marco Senzolo

This article belongs to the Special Issue Challenges in the Management of Hepatocellular Carcinoma in Cirrhotics with Clinically Significant Portal Hypertension

Hepatoma Res 2023;9:49. DOI: 10.20517/2394-5079.2023.88

Systematic Review | Published on: 20 Nov 2023

Opinion

Perspective of tumor heterogeneity for treatments of intrahepatic cholangiocarcinoma with intrahepatic lithiasis

Wenjie Hou, ... Qiqiang Zeng

This article belongs to the Special Issue Challenges and Opportunities for Treating Intrahepatic Cholangiocarcinoma

Hepatoma Res 2023;9:35. DOI: 10.20517/2394-5079.2023.40

Opinion | Published on: 30 Jul 2023

Letter to Editor

Systemic treatment for hepatocellular carcinoma beyond milan criteria on the waitlist: is it time for a neoadjuvant therapy?

Bianca Magro, ... Salvatore Gruttadauria

This article belongs to the Special Issue Liver Transplantation for Hepatocellular Carcinoma: Up to Date

Hepatoma Res 2023;9:23. DOI: 10.20517/2394-5079.2023.38

Letter to Editor | Published on: 4 Jun 2023

Commentary

Ethnic disparities in the epidemiology, treatment, and outcome of patients with hepatocellular carcinoma in the United States

Mohammad Saeid Rezaee-Zavareh, ... Ju Dong Yang

This article belongs to the Special Issue Racial/Ethnic Differences in Liver Cancer

Hepatoma Res 2023;9:18. DOI: 10.20517/2394-5079.2023.10

Commentary | Published on: 18 May 2023

Perspective

Liver Transplantation for perihilar cholangiocarcinoma. Do we need to move forward?

Cristina Dopazo, Ramón Charco

This article belongs to the Special Issue Advances in Surgical and Multimodality Treatment for (of) Cholangiocarcinoma

Hepatoma Res 2023;9:10. DOI: 10.20517/2394-5079.2022.75

Perspective | Published on: 28 Mar 2023

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