Topic: Bioactive Materials for Tissue Regeneration

Decades ago, inert materials were considered the first choice of materials for use in the body as they may generate a minimal tissue response. Recent advances have shown that bioactive materials directly contact cells and adapt to the microenvironment, potentially regulating cellular and tissue responses and influencing tissue regeneration. Bioactive materials, presented in various forms (hydrogels, scaffolds, and bioinks et al.), are crucial to guide and regulate cell behaviors, especially stem cells, in terms of adhesion, proliferation, differentiation, and multicellular organization. The microstructure of the biomaterials plays a key role in the tissue regeneration process as it determines how cells sense the residential niche. Researchers have harnessed biomaterials' biochemical and physical properties to stimulate angiogenesis, neuron regeneration, and even tumor suppression spontaneously with tissue regeneration.

It is still challenging to repair and construct large and complex tissue/organs despite the huge progress in developing bioactive materials. A thorough and fundamental understanding of the interplay among biomaterials, cells, and microenvironment is required to guide the design and application of the next generation of bioactive materials.

This Special Issue will focus on novel bioactive materials and microstructure for tissue engineering and regenerative medicine. We welcome manuscripts from various disciplines and particularly encourage researchers who have made significant progress the repairing malfunctioned tissues and organs through materials science and engineering.

The Special Issue will include (not limited to) the following subjects:
● Biomaterials for tissue/organ regeneration
● Tissue Engineering
● 3D Bioprinting
● Microstructure
● Stem cells

Biomaterials, stem cells, tissue engineering, regenerative medicine

30 Sep 2023