Special Issue

Topic: Genetics and Genomics of Cancer
A Special Issue of Journal of Translational Genetics and Genomics
ISSN 2578-5281 (Online)
Submission deadline: 30 Apr 2019
Guest Editor(s)
Special Issue Introduction
Tumorigenesis is a multistep process that begins with the transformation of a single cell which acquires one or more of the “hallmarks of cancer”. Cells acquire these characteristics through numerous somatic mutations caused by errors of DNA replication, the action of exogenous mutagens or endogenous DNA damage, leading to the activation of oncogenes and the inactivation of tumour suppressors. Different tumours differ with respect to their mutational spectra and these patterns of mutation are often characteristic of the tumour in question. Genetic susceptibility to cancer is also conferred by inherited variants of cancer predisposition genes. As whole exome/genome sequencing becomes commonplace in a clinical genetics/personalised genomics setting, we are gradually developing an understanding of the role of both inherited and acquired variants in tumorigenesis. We plan to publish reviews of the molecular genetics of human cancers which we hope will allow the reader to compare and contrast some of the 100+ different human cancers in terms of their underlying mutational spectra.
Keywords
Cancer genetics, genomics, genome, mutation, mutational spectra, personalized medicine
Submission Deadline
30 Apr 2019
Submission Information
For Author Instructions, please refer to https://oaepublish.com/jtgg/author_instructions
For Online Submission, please login at https://oaemesas.com/login?JournalId=jtgg
Submission Deadline: 30 Apr 2019
Contacts: Lucia Liu, Assistant Editor, editor001@jtggjournal.com
Published Articles
Open Access Review
Overview of liposarcomas and their genomic landscape
This article belongs to the Special Issue Genetics and Genomics of Cancer
J Transl Genet Genom 2019;3:8.
Available online: 21 May 2019
Open Access Review
Genomics of cutaneous melanoma: focus on next-generation sequencing approaches and bioinformatics
This article belongs to the Special Issue Genetics and Genomics of Cancer
J Transl Genet Genom 2019;3:7.
Available online: 1 Apr 2019
Open Access Review
Evolution of the prostate cancer genome towards resistance
This article belongs to the Special Issue Genetics and Genomics of Cancer
J Transl Genet Genom 2019;3:5.
Available online: 11 Mar 2019
Open Access Review
The somatic clinico-genomics of localized, non-indolent prostate cancer
This article belongs to the Special Issue Genetics and Genomics of Cancer
J Transl Genet Genom 2018;2:21.
Available online: 17 Dec 2018
Open Access Review
Genomics and genetics of clear cell renal cell carcinoma: a mini-review
This article belongs to the Special Issue Genetics and Genomics of Cancer
J Transl Genet Genom 2018;2:17.
Available online: 5 Nov 2018
Open Access Review
Radiogenomics of medulloblastoma: imaging surrogates of molecular biology
This article belongs to the Special Issue Genetics and Genomics of Cancer
J Transl Genet Genom 2018;2:15.
Available online: 23 Oct 2018
Open Access Review
Clinical and therapeutic implications of melanoma genomics
This article belongs to the Special Issue Genetics and Genomics of Cancer
J Transl Genet Genom 2018;2:14.
Available online: 27 Sep 2018
Open Access Review
Molecular genetics of Ewing sarcoma, model systems and finding novel (immuno-) therapeutic targets
This article belongs to the Special Issue Genetics and Genomics of Cancer
J Transl Genet Genom 2018;2:10.
Available online: 15 Jul 2018
Open Access Review
Parathyroid carcinoma
This article belongs to the Special Issue Genetics and Genomics of Cancer
J Transl Genet Genom 2018;2:5.
Available online: 21 May 2018