Topic: Therapeutic Potential of Milk and Plant-Derived Extracellular Vesicles
A Special Issue of Extracellular Vesicles and Circulating Nucleic Acids
ISSN 2767-6641 (Online)
Submission deadline: 31 Mar 2024
Guest Editor(s)
Elisa Panzarini
Associate Professor, Department of Biological Sciences and Technologies, University of Salento, Lecce, Italy.
Special Issue Introduction
In recent years, there has been a tremendous increase in interest regarding milk and plant-derived extracellular vesicles (EVs). Transmission electron microscopy (TEM) has revealed that these EVs are similar to those of animal origin: lipoprotein structures of heterogeneous dimensions carrying several bioactive molecules, including lipids, proteins, and genetic material, particularly miRNAs. Plants release various types of vesicles that play relevant biological roles in health and disease development, suggesting their potential for formulating new functional food and nutraceuticals for both humans and animals, as EVs from food might contribute to the overall body homeostasis. Likewise, studies have shown that EVs abundant in milk have a beneficial effect on human health at multiple levels, including intestinal health, bone/muscle metabolism, and microbiota regulation, due to their important functions, such as immune regulation, anti-bacterial infection, and anti-oxidative actions.
The interesting feature of milk and plant-derived EVs are the ability to cross mammalian barriers without inducing side effects, conversely to conventional synthetic drug delivery systems. As a result, they can act as efficient and biocompatible natural drug carriers with low immunogenicity, good biocompatibility, and stability, rendering them excellent candidates for the delivery of therapeutic agents or poorly soluble natural compounds. Milk and plant-derived EVs can be further engineered for targeted delivery to improve the circulation time or enhance local drug concentrations. Despite the great potential of milk and plant-derived EVs as therapeutic tools for combating a plethora of diseases, some confusion is still present.
We welcome submissions of Original Research and Review articles that focus on, but are not limited to, the following:
● The applicative aspects of milk and plant-derived EVs as therapeutics;
● The methods suitable to isolate and characterize milk and plant-derived EVs.
We hope that the collected papers covering different aspects of milk and plant-derived EVs will contribute to the advancement of EVs-based therapeutic solutions.
The cover image is reproduced from Rezaie, J et al., 2022, Raimondo, S et al., 2022, Alessandro, R et al., 2021, Mathivanan, S et al., 2020, Chi, X et al., 2021.
The interesting feature of milk and plant-derived EVs are the ability to cross mammalian barriers without inducing side effects, conversely to conventional synthetic drug delivery systems. As a result, they can act as efficient and biocompatible natural drug carriers with low immunogenicity, good biocompatibility, and stability, rendering them excellent candidates for the delivery of therapeutic agents or poorly soluble natural compounds. Milk and plant-derived EVs can be further engineered for targeted delivery to improve the circulation time or enhance local drug concentrations. Despite the great potential of milk and plant-derived EVs as therapeutic tools for combating a plethora of diseases, some confusion is still present.
We welcome submissions of Original Research and Review articles that focus on, but are not limited to, the following:
● The applicative aspects of milk and plant-derived EVs as therapeutics;
● The methods suitable to isolate and characterize milk and plant-derived EVs.
We hope that the collected papers covering different aspects of milk and plant-derived EVs will contribute to the advancement of EVs-based therapeutic solutions.
The cover image is reproduced from Rezaie, J et al., 2022, Raimondo, S et al., 2022, Alessandro, R et al., 2021, Mathivanan, S et al., 2020, Chi, X et al., 2021.
Submission Deadline
31 Mar 2024
Submission Information
For Author Instructions, please refer to https://www.oaepublish.com/evcna/author_instructions
For Online Submission, please login at https://oaemesas.com/login?JournalId=evcna&SpecialIssueId=evcna230628
Submission Deadline: 31 Apr 2024
Contacts: Inga Ren, Assistant Editor, EVCNA-editor@oaemesas.com
