The Online International Symposium "Lifestyle, Dietary Patterns and Nutrition Status with Risk Factors of Hepatocellular Carcinoma" Organized by Hepatoma Research Has Been Successfully Held

The online international symposium "Lifestyle, Dietary Patterns and Nutrition Status with Risk Factors of Hepatocellular Carcinoma" organized by Hepatoma Research and chaired by Prof. Giuliano Ramadori from University Medical Center Göttingen, Göttingen, Germany, was successfully held on April 25, 2024.

Five outstanding international Guest Speakers delivered exceptional speeches and shared their innovative insights during the webinar.

Prof. Giuliano Ramadori delivered a comprehensive presentation focusing on "The distinction between the Mediterranean diet and regional lifestyles highlights its timeless appeal."

Topic: Montegiorgio, Crevalcore, North-Karelia and the Mediterranean Diet

Prof. Stefano Bellentani, Consultant Gastroenterologist and Hepatologist, from the Italian Liver Foundation, Basovizza, Italy, and Chief of Gastroenterology & Hepatology Service at Clinica Santa Chiara-Locarno, Switzerland, presented an evidence-based diet focusing on healthy eating patterns. This diet emphasizes the consumption of minimally or unprocessed foods, low in sugar and saturated fat, while being rich in polyphenols and healthy fats such as mono- and omega-3 polyunsaturated fats, as an effective treatment for Metabolic Associated Fatty Liver Disease (MAFLD).

Topic: Lifestyle, Mash-cirrhosis and HCC

Prof. Chun-Feng Qu, a researcher from the National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences in Beijing, China, discussed ceramide levels and species in hepatocytes infected with PreS variants isolated from HBsAg-seronegative patients with hepatocellular carcinoma (HCC), and the effects of ceramide on the development of autochthonous HCC in murine models.

Topic: Occult Infection with Hepatitis B Virus PreS Variants Synergistically Promotes Hepatocellular Carcinoma Development in a High-Fat Diet Context by Generating Abnormal Ceramides

Dr. Marco Giacchetto, a Hepatology Researcher involved in the NRRP project SAMOTHRACE at the Sicilian MicronanoTech Research and Innovation Center in Palermo, Italy, delivered an informative presentation. He discussed the correlation between metabolic diseases, particularly diabetes and obesity, and an elevated risk of HCC, along with other dysmetabolic traits like hypertension and dyslipidemia. Dr. Giacchetto also emphasized the role of lifestyle-related modifiable factors, such as specific dietary choices, dietary patterns, and physical activity, in reducing the risk of HCC.

Topic: Nutritional Status and Lifestyle Factors as Risk Factors for HCC in the Transplant Setting

Prof. Orlando Musso, Principal Investigator at the Institute of Nutrition, Metabolism, and Cancer (NuMeCan), INSERM, University of Rennes, INRAe, France, provided valuable scholarly insights during the webinar. He outlined views on “Fibrous Nests: ECM & STEM HCC subclasses” and highlighted that tumors with the best prognosis maintain the metabolic liver zonation.

Topic: “Fibrous Nests” in Hepatocellular Carcinoma, a Tumor Niche Enriched in Wnt Signals and Cancer Progenitor/Stem Cells

The Editorial Office of Hepatoma Research extends its sincere gratitude to Prof. Giuliano Ramadori, the Chair, for his exceptional organization of this webinar. We also express our heartfelt appreciation to all the Guest Speakers for their substantial contributions, which were instrumental in making this webinar a resounding success.

Finally, we call for papers for the Webinar Issue "Lifestyle, Dietary Patterns and Nutrition Status with Risk Factors of Hepatocellular Carcinoma" led by Prof. Giuliano Ramadori. Welcome to submit your manuscript at: https://oaemesas.com/login?JournalId=hr

We welcome more researchers and scholars to join the journal’s future webinars! Stay tuned for more wonderful sessions: https://www.oaepublish.com/hr/webinars

Editor: Ada Zhong
Language Editor: Catherine Yang
Production Editor: Yan Zhang
Respectfully Submitted by the Editorial Office of Hepatoma Research