The aim of Liver Nexus is to bridge molecular biology, clinical hepatology, bioengineering, data science, and public health to accelerate discovery and improve patient outcomes in liver-related diseases. The journal emphasizes cross-disciplinary collaboration and systems-level understanding of liver function and pathology, recognizing the liver as a central nexus in metabolism, immunity, detoxification, and systemic disease.

The scope of the journal includes basic science, clinical and translational aspects of liver structure, function, pathology, physiopathology, psychopharmacology, diagnostics and therapeutics. Specifically, we publish articles relevant but not limited to:

The scope of the journal includes, but is not limited to:

• Liver histology, hepatobiliary physiology, development, regeneration, aging and pathology

• Gut–liver axis, bile acids, intestinal microbiome, and immunometabolism in hepatic health and disease

• Molecular and cellular mechanisms of acute and chronic liver disease

• Metabolic dysfunction-associated steatotic liver disease/steatohepatitis (MASLD/MASH), alcohol-related liver disease, viral hepatitis, autoimmune liver disorders, drug-induced liver injury, rare liver disorders, liver health in extra-hepatic and systemic conditions

• Liver steatosis, steatohepatitis, fibrosis, cirrhosis

• Cholestasis, portal hypertension, liver failure

• Primary hepatic and biliary cancers and liver metastases

• Liver transplantation, organ preservation, and regenerative medicine

• Stem cells, organoids, tissue engineering, and bioartificial liver systems

• Diagnostic innovations, biomarkers, imaging, and digital pathology

• Artificial intelligence, machine learning, and big data in hepatology

• Precision therapeutics, pharmacology in hepatology, drug discovery, and clinical trials

• Epidemiology, prevention, and health policy regarding liver diseases