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EVCNA Expert Interview Series XII - Dr. Juan Manuel Falcón-Pérez

Published on: 3 Nov 2025 Viewed: 10

On June 12, 2023, the Editorial Office of Extracellular Vesicles and Circulating Nucleic Acids (EVCNA) had an exclusive interview with Dr. Juan Manuel Falcón-Pérez. During the discussion, he shared his thoughts on being honored with the ISEV 2023 Special Achievement Award and his current research projects on oral progenitor cell line-derived small extracellular vesicles for wound treatment. Dr. Weiliang Xia, a professor at Biomedical Engineering and Med-X Research Insitute, Shanghai Jiao Tong University, Shanghai, China, hosted the interview. Dr. Juan Manuel Falcón-Pérez is IKERBSQUE Research Professor. He is also the group leader of the Exosomes Lab and Head of the Metabolomics Platform at CIC bioGUNE-BRTA, Bilbao, Spain. Throughout the interview, Dr. Falcón-Pérez shared details about his research journey, ongoing projects, and progress, and elaborated on some of his key contributions and notable projects. Additionally, Dr. Falcón-Pérez talked about his future research plans and goals and provided several helpful suggestions for researchers to begin their journey in this field.

Watch the following video for expert insights from Dr. Juan Manuel Falcón-Pérez:

Interview Questions:

Q1: First of all, congratulations on winning the ISEV 2023 Special Achievement Award! Could you please share your thoughts and feelings about receiving this award, as well as some highlights of your research progress and achievements?
Q2: We are aware of your current research on oral progenitor cell line-derived small extracellular vesicles as a treatment for wounds. What advantages do EVs offer compared to other treatment approaches?
Q3: There is growing interest in the reproducibility of extracellular vesicle studies. Could you please share the main challenges and potential solutions for improving reproducibility in this field?
Q4: As reliable biomarkers, what are the prospects and challenges for using extracellular vesicles in clinical applications?
Q5: As we know, you have made significant contributions to and participated in various areas of EV research since 2005. Could you elaborate on some of your key contributions and notable projects over the years?
Q6: What are your specific plans for future research?
Q7: What piece of advice will you give to scientists to starting their journey in this field?

About Dr. Juan Manuel Falcón-Pérez:

Dr. Juan Manuel Falcón-Pérez, IKERBASQUE Research Professor Group Leader of Exosomes Lab and Head of Metabolomics Platform at CIC bioGUNE-BRTA, Bilbao, Spain.
Dr Falcón-Perez is member of ISEV since 2012. He has been Chair of annual ISEV meeting in Barcelona 2018 and member of IOC of Rotterdam 2016 and Japan 2019, ISEV annual meetings.
Dr Falcón-Pérez was Board member since 2016 starting in the Educational Committee with contributions to the elaboration of several ISEV educational material including elaboration of surveys, posters, guidelines and SOPs.
He participated in the creation and is currently co-chair of the Rigor and Standardization committee. He also participated in the foundation and is currently deputy editor of the Journal of Extracellular Biology.
Since 2005 Juan Manuel Falcón-Pérez has made seminal contributions and participations in different areas of EVs including method comparisons (for proteins, RNAs and metabolites), method development (EV labelling and single-vesicle analysis), also biomarker discovery and therapeutics focused in structural, molecular ( applying many omics technologies) and functional analysis by studying biodistribution, glycosylation and EV engineering. Applications of EVs in a broad range of experimental models including several cellular systems (mouse, rat, flies, human) and body fluids such as urine, blood, cerebrospinal fluid, ascites, BALF, endometrial fluid in various biomedical areas including cancer (prostate, bladder, breast, pancreatic, CCR, HCC), metabolic, neurodegenerative and infectious diseases.

Editor: Yan Lei
Production Editor: Ting Xu
Respectfully Submitted by the Editorial Office of Extracellular Vesicles and Circulating Nucleic Acids

Extracellular Vesicles and Circulating Nucleic Acids
ISSN 2767-6641 (Online)
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