fig5

Figure 5. Probiotic strain abundances in the SHIME® model. (A) High inter-individual differences in relative abundance of Bb; (B) Relative abundance of Lf. From samples after 48 h in the ex vivo SHIME® model for each infant fecal inoculum. Blank: No probiotics; iPF: intact protein formula; GOS: galactooligosaccharides; eHF: extensively hydrolyzed formula; Bb: B. breve DSMZ 32583; Lf: L. fermentum CECT 5716; Lf + Bb: both probiotics added; VD: fecal inoculum derived from vaginally delivered infant; CS: fecal inoculum derived from cesarean-delivered infant; SHIME: Simulator of the Human Intestinal Microbial Ecosystem.