fig4

Figure 4. Infant microbiome composition in the SHIME® gut model. (A) Family level taxonomic profile; (B) Genus level taxonomic profile; (C) Relative abundance of all detected Bifidobacterium strains from samples after 48 h in the ex vivo fermentors for 8 different media compositions for each infant fecal inoculum. Blank: No probiotics; iPF: intact protein formula; GOS: galactooligosaccharides; eHF: extensively hydrolyzed formula; Bb: B. breve DSM 32583; Lf: L. fermentum CECT 5716; Lf + Bb: both probiotics added; VD: fecal inoculum derived from vaginally delivered infant; CS: fecal inoculum derived from cesarean-delivered infant; SHIME: Simulator of the Human Intestinal Microbial Ecosystem.