fig5

Figure 5. Effects of B. longum subsp. infantis on the diversity of the bifidobacterial community in female and male mice. (A and B) Chao 1 and Shannon index of total bacteria in female mice; (C) β-diversity of Bifidobacterium composition in female mice; (D) heatmap of bifidobacterial composition in female mice. The relative abundance of Bifidobacterium in each group was row normalization. The blue circle means lower relative abundance and the red circle means higher relative abundance; (E-J) the significant difference of Bifidobacterium in female mice; (K and L) Chao 1 and Shannon index of total bacteria in male mice; (M) β-diversity of bifidobacterial community in male mice, respectively; (N) heatmap of bifidobacterial composition in male mice. The relative abundance of Bifidobacterium in each group was row normalization. The blue circle means lower relative abundance and the red circle means higher relative abundance; (O-T) the significant difference of Bifidobacterium in male mice. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001, compared to corresponding to the control group. The mean ± SEM (n = 8 per group) was used to represent the data. SEM: Error of the mean.