fig6

Figure 6. Impact of sketching k-mer on the estimation of k-mer-based Bray-Curtis distances. (A) Absolute differences between the exact k-mer-based Bray-Curtis distances and sketched Bray-Curtis distances for an increasing Sketch size; (B) Exact k-mer-based against the sketched Bray-Curtis distances (k = 30bp) obtained for a simulated dataset of 100 metagenomes simulated at a sequencing depth of 5 million paired reads using the HiSeq sequencing error model.