fig5

Figure 5. Impact of decreasing taxonomic diversity on the correlation between expected taxonomic and k-mer-based beta-diversity metric. Spearman correlations between the expected taxonomic and k-mer-based Bray-Curtis distance for simulated communities containing 50 taxa from all possible taxonomic classes (“All taxa”), from the Actinomycetes class (“Same class”) or from the Mycobacterium family (“Same family”). Simulated metagenomes were generated to simulate a sequencing depth of (A) 500K paired reads; (B) 1 Million paired reads; (C) 5 Million paired reads; or (D) 10 Million paired reads.