fig7

Gastric organoid/organ-on-a-chip platforms for disease modeling and personalized medicine: a review

Figure 7. Multiorgan-on-a-chip. (A) Front and cross-sectional views of the microfluidic device for modeling the interactions of the stomach and other organs; (B) Schematic of the liver-stomach-intestine multiorgan model formed by organoids; (C) Immunostaining analysis of specific markers for different organs (albumin for liver; Muc2 and lysozyme for intestine; and Muc5ac and H+/K+ ATPase for stomach). Scale bars: 200 μm. (A-C) is reproduced from Ref.[74]. Copyright 2018, John Wiley & Sons. ALB: Albumin; ECAD: E-cadherin; Muc2: Mucin-2; DAPI: 4',6-Diamidino-2-phenylindole.