fig6
From: Gastric organoid/organ-on-a-chip platforms for disease modeling and personalized medicine: a review
Figure 6. OoC for gastric cancer modeling. (A) Vascularized tumor-on-a-chip for the prediction of clinical responses to VEGFR2-targeted therapy; (B) Immunofluorescence staining images of pVEGFR2, F-actin, CD31, and DAPI in the PDOs of responders and nonresponders. Scale bars: 100 μm. (A) and (B) were reproduced from Ref.[73]. Copyright 2023, John Wiley & Sons. PDO: Patient-derived organoid; VEGFR2: Vascular Endothelial Growth Factor Receptor 2; CD31: Cluster of Differentiation 31; DAPI: 4',6-diamidino-2-phenylindole; OoC: organ-on-a-chip.
