fig5
From: Gastric organoid/organ-on-a-chip platforms for disease modeling and personalized medicine: a review
Figure 5. Stomach-on-a-chip for host-pathogen interaction modeling. (A) Human stomach microphysiological system for studying epithelial and immune responses to H. pylori infection. Scale bars: 250 μm (top) and 100 μm (bottom); (B) Impact of H. pylori infection on the expression of TFF1 and the ability to recruit PBMCs of the human gastric epithelium. Scale bars: 20 μm (left) and 250 μm (right). (A and B) is reproduced from Ref.[23] under the terms of the CC BY 4.0 License. MPS: Micro-physiological system; hAO: human antral organoids; gMSC: gastric mesenchymal stromal cell; PBMC: peripheral blood mononuclear cell; TFF1: trefoil factor peptide 1; H. pylori: Helicobacter pylori.
