fig3

Figure 3. Collagen and collagen-derived microscale carriers for cell delivery. (A) Cell viability detection and confocal imaging of rADSCs encapsulated in crosslinked gelatin microspheres: (i) Live/dead assay demonstrated that most cells were still viable. (ii) After 7 days of culture, rADSCs spread out, and a large number of filopodia structures formed. Figure 3A is adapted in part from Ref.^[79]. Reused under the terms of the Creative Commons Attribution License (CC BY); (B) Collagen microspheres carrying DRGs and OPCs co-culture. (i) The green-circled area indicates the collagen microspheres. (ii) and (iii) On the collagen microspheres, OPCs differentiate into OLs, and the OLs surround the DRGs. Figure 3B is adapted in part from Ref.^[81]. Reused under the terms of the Creative Commons Attribution License (CC BY). rADSC: Rat Adipose-Derived Stem Cell; DRG: dorsal root ganglion; OPC: oligodendrocyte precursor cell; OL: oligodendrocyte.