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Mitochondria-targeting amphiphilic polymers enable idebenone to promote neuronal regeneration following spinal cord injury

Figure 1. Synthesis and characterization of SP@I, P@I. (A) Schematic diagram of synthesis of SP@I; (B) Particle size distribution of SP@I, P@I; (C) Zeta potential of SP@I, P@I; (D) Representative TEM image of SP@I, P@I. Scale bar is 50 nm; (E) FT-IR Spectrum of SS31, P@I, and SP@I. (F) 1H-NMR Spectrum of SP@I. EDC: NHS: TEM: transmission electron microscopy; FT-IR: Fourier-transform infrared spectroscopy; 1H-NMR: 1H nuclear magnetic resonance.