fig2

Figure 2. The regulatory landscape of m6A modification in periodontitis and related disease models. (Created with Figdraw; ID: AYWWUd8ee8). PDLC: Periodontal ligament cell; BMSC: bone marrow mesenchymal stem cell; YTHDC1: YTH N6-methyladenosine RNA binding protein C1; IGF2BP: insulin-like growth factor 2 mRNA-binding proteins; METTL3: methyltransferase-like 3; WTAP: Wilms tumor 1-associated protein; SLC39A9: solute carrier family 39 member 9; TNFAIP3: TNF alpha induced protein 3; YAP: Yes1 associated transcriptional regulator; Runx2: RUNX family transcription factor 2; TP53BP1: tumor protein p53 binding protein 1; FTO: fat mass and obesity-associated protein; ALKBH5: AlkB homolog 5; TLR9: toll-like receptor 9; MAPK: mitogen-activated protein kinase; CDK2: cyclin dependent kinase 2; HK1: hexokinase 1; ZEB1: zinc finger E-box binding homeobox 1; m6A: N6-methyladenosine.