fig2

Figure 2. Meta-analysis of the association between the rs10919563 polymorphism in the PTPRC gene and response to TNF inhibitor treatment in patients with rheumatoid arthritis. The three genetic models showed statistically significant associations: the allelic model (A), the recessive model for allele A (B), and the recessive model for allele G (C). The allelic and recessive models of the G allele were analyzed using a random-effects model, while the recessive model was analyzed using a fixed-effects model. The combined analysis of the polymorphisms was performed using the Mantel-Haenszel meta-analysis, applying fixed- and random-effects models through the metabin function. Original figure created by the authors for this study.