fig2
Figure 2. Spatial distribution of Scube2-creER- and Cthrc1-creER-labeled fibroblasts. In homeostasis, Scube2-creER-labeled fibroblasts are located within the alveolar septa, where they support AT2 cells. During fibrosis, Cthrc1-creER‑labeled fibroblasts localize to the alveolar lumen, where they secrete collagen I and drive intra-alveolar fibrosis.