fig2

The crucial role of alveolar fibroblasts in pulmonary fibrosis

Figure 2. Spatial distribution of Scube2-creER- and Cthrc1-creER-labeled fibroblasts. In homeostasis, Scube2-creER-labeled fibroblasts are located within the alveolar septa, where they support AT2 cells. During fibrosis, Cthrc1-creER‑labeled fibroblasts localize to the alveolar lumen, where they secrete collagen I and drive intra-alveolar fibrosis.

Journal of Translational Genetics and Genomics
ISSN 2578-5281 (Online)
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