REFERENCES

1. Singer M, Deutschman CS, Seymour CW, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016;315:801-10.

2. Rudd KE, Johnson SC, Agesa KM, et al. Global, regional, and national sepsis incidence and mortality, 1990-2017: analysis for the Global Burden of Disease Study. Lancet. 2020;395:200-11.

3. Huang M, Cai S, Su J. The Pathogenesis of sepsis and potential therapeutic targets. Int J Mol Sci. 2019;20:5376.

4. Rocheteau P, Chatre L, Briand D, et al. Sepsis induces long-term metabolic and mitochondrial muscle stem cell dysfunction amenable by mesenchymal stem cell therapy. Nat Commun. 2015;6:10145.

5. Singh SB, Lin HC. Role of intestinal alkaline phosphatase in innate immunity. Biomolecules. 2021;11:1784.

6. Han Y, Chen J, Li Z, Chen H, Qiu H. Recent progress and prospects of alkaline phosphatase biosensor based on fluorescence strategy. Biosens Bioelectron. 2020;148:111811.

7. Iluz-Freundlich D, Grubert Van Iderstine M, Uhanova J, Zhang M, Knowles C, Minuk GY. Low serum alkaline phosphatase levels in patients with chronic liver diseases: Possible contributions to disease pathogenesis. Clin Res Hepatol Gastroenterol. 2021;45:101694.

8. Lee JH, Cho AR, Lee YJ. Relationship between serum alkaline phosphatase and low muscle mass index among Korean adults: a nationwide population-based study. Biomolecules. 2021;11:842.

9. Kunutsor SK, Apekey TA, Khan H. Liver enzymes and risk of cardiovascular disease in the general population: a meta-analysis of prospective cohort studies. Atherosclerosis. 2014;236:7-17.

10. Cheung BM, Ong KL, Wong LY. Elevated serum alkaline phosphatase and peripheral arterial disease in the United States National Health and Nutrition Examination Survey 1999-2004. Int J Cardiol. 2009;135:156-61.

11. Kim JH, Lee HS, Park HM, Lee YJ. Serum alkaline phosphatase level is positively associated with metabolic syndrome: a nationwide population-based study. Clin Chim Acta. 2020;500:189-94.

12. Mirjačić Martinović K, Vuletić A, Tišma Miletić N, et al. Increased circulating monocyte MDSCs positively correlate with serum Interleukin-10 in metastatic melanoma patients. Innate Immun. 2023;29:37-44.

13. Katasako A, Sasaki S, Raita Y, et al. Association between serum alkaline phosphatase and bacteraemia in haemodialysis outpatients: a multicentre retrospective cross-sectional study. BMJ Open. 2022;12:e058666.

14. Cheung BM, Ong KL, Cheung RV, et al. Association between plasma alkaline phosphatase and C-reactive protein in Hong Kong Chinese. Clin Chem Lab Med. 2008;46:523-7.

15. Kerner A, Avizohar O, Sella R, et al. Association between elevated liver enzymes and C-reactive protein: possible hepatic contribution to systemic inflammation in the metabolic syndrome. Arterioscler Thromb Vasc Biol. 2005;25:193-7.

16. Emdin CA, Khera AV, Kathiresan S. Mendelian randomization. JAMA. 2017;318:1925-6.

17. Cohen JC, Boerwinkle E, Mosley TH Jr, Hobbs HH. Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. N Engl J Med. 2006;354:1264-72.

18. Li X, Hastie AT, Hawkins GA, et al. eQTL of bronchial epithelial cells and bronchial alveolar lavage deciphers GWAS-identified asthma genes. Allergy. 2015;70:1309-18.

19. Zeng L, Tang H, Chen J, et al. Causal association of lipoprotein-associated phospholipids on the risk of sepsis: a Mendelian randomization study. Front Endocrinol. 2023;14:1275132.

20. Hu Y, Cheng X, Mao H, Chen X, Cui Y, Qiu Z. Causal effects of genetically predicted iron status on sepsis: a two-sample bidirectional Mendelian randomization study. Front Nutr. 2021;8:747547.

21. Zhang Z, Yin Y, Chen T, et al. Investigating the impact of human blood metabolites on the Sepsis development and progression: a study utilizing two-sample Mendelian randomization. Front Med. 2023;10:1310391.

22. Zhi F, Ma JW, Ji DD, Bao J, Li QQ. Causal associations between circulating cytokines and risk of sepsis and related outcomes: a two-sample Mendelian randomization study. Front Immunol. 2024;15:1336586.

23. Fang W, Chai C, Lu J. The causal effects of circulating cytokines on sepsis: a Mendelian randomization study. PeerJ. 2024;12:e16860.

24. Pollard TJ, Johnson AEW, Raffa JD, Celi LA, Mark RG, Badawi O. The eICU Collaborative Research Database, a freely available multi-center database for critical care research. Sci Data. 2018;5:180178.

25. Skrivankova VW, Richmond RC, Woolf BAR, et al. Strengthening the reporting of observational studies in epidemiology using mendelian randomization: the STROBE-MR statement. JAMA. 2021;326:1614-21.

26. Hemani G, Zheng J, Elsworth B, et al. The MR-Base platform supports systematic causal inference across the human phenome. eLife. 2018;7:e34408.

27. Kamat MA, Blackshaw JA, Young R, et al. PhenoScanner V2: an expanded tool for searching human genotype-phenotype associations. Bioinformatics. 2019;35:4851-3.

28. Burgess S, Thompson SG. Bias in causal estimates from Mendelian randomization studies with weak instruments. Stat Med. 2011;30:1312-23.

29. Burgess S, Thompson SG. Interpreting findings from Mendelian randomization using the MR-Egger method. Eur J Epidemiol. 2017;32:377-89.

30. Bowden J, Del Greco M F, Minelli C, et al. Improving the accuracy of two-sample summary-data Mendelian randomization: moving beyond the NOME assumption. Int J Epidemiol. 2019;48:728-42.

31. Bowden J, Davey Smith G, Burgess S. Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression. Int J Epidemiol. 2015;44:512-25.

32. Zhang CY, Zhang HH, Zhao SL, et al. Clinical value of alkaline phosphatase on the surface membrane of neutrophils for prediction of bacteremia in patients with systemic inflammatory response syndrome. Diagn Microbiol Infect Dis. 2021;100:114105.

33. Park HM, Lee JH, Lee YJ. Positive association of serum alkaline phosphatase level with severe knee osteoarthritis: a nationwide population-based study. Diagnostics. 2020;10:1016.

34. Webber M, Krishnan A, Thomas NG, Cheung BM. Association between serum alkaline phosphatase and C-reactive protein in the United States National Health and Nutrition Examination Survey 2005-2006. Clin Chem Lab Med. 2010;48:167-73.

Journal of Translational Genetics and Genomics
ISSN 2578-5281 (Online)
Follow Us

Portico

All published articles are preserved here permanently:

https://www.portico.org/publishers/oae/

Portico

All published articles are preserved here permanently:

https://www.portico.org/publishers/oae/