fig5

EQTL Mendelian randomization to identify genetic insights and regulatory mechanisms in benign prostatic hyperplasia

Figure 5. Colocalization analysis. (A-E) Regional association plots comparing GWAS and eQTL signals for C2, GUCY1B2, OLFM4, ITPR1, and KLHL36. Left panels display the relationship between GWAS and eQTL association signals, whereas right panels show regional association patterns across genomic coordinates. eQTL: Expression quantitative trait locus; GWAS: Genome-wide association study; C2: complement component 2; GUCY1B2: guanylate cyclase 1 soluble subunit beta 2; OLFM4: olfactomedin 4; ITPR1: inositol 1,4,5-trisphosphate receptor type 1; KLHL36: kelch like family member 36.

Journal of Translational Genetics and Genomics
ISSN 2578-5281 (Online)
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