fig2
Figure 2. Integrated screening and identification of MIE-active compounds and their TPs. MIE: Molecular initiating event; LC–HRMS: liquid chromatography–high‑resolution mass spectrometry; PUCA: protein-affinity purification coupled with nontargeted mass spectrometry approaches; ER: estrogen receptor; TP: transformation product; LC–MS: liquid chromatography–mass spectrometry.
