fig2

6-PPD quinone-inhibited retinoic acid synthesis mediates toxicity through feedback loop between ALH-3/DHS-19-SEX-1 axis and intestinal signals in <i>Caenorhabditis elegans</i>

Figure 2. Effect of RNAi of alh-3 and dhs-19 on 6-PPDQ toxicity in inducing ROS generation (A); decreasing locomotion (B); and reducing brood size (C). Exposure concentration of 6-PPDQ was 10 μg/L. **P < 0.01. RNAi: RNA interference; 6-PPDQ: N’-(1,3-dimethylbutyl)-N’-phenyl-p-phenylenediamine quinone.

Journal of Environmental Exposure Assessment
ISSN 2771-5949 (Online)

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