fig5

Benchmark dose modeling to define permissible exposure levels for environmental cadmium

Figure 5. Cadmium excretion rates associated with a 5% eGFR reduction. Bootstrap dose-response model averaging with 200 repeats for eGFR-Cd excretion as ECd/Ecr (A) and ECd/Ccr (C); BMDL/BMDU values for Cd excretion as ECd/Ecr (B) and ECd/Ccr (E). Model weights for Cd excretion as ECd/Ecr (C) and ECd/Ccr (F). × and △ represent male and female participants, respectively[126]. eGFR: Estimated glomerular filtration rate; Cd: cadmium; Ecr: creatinine excretion; BMDL: benchmark dose limit; ECd: urinary Cd; BMDU: upper 95% confidence bound of BMD.

Journal of Environmental Exposure Assessment
ISSN 2771-5949 (Online)

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