fig2
From: Aging triggers mitochondrial, endoplasmic reticulum, and metabolic stress responses in the heart
Figure 2. Aging induces mitochondrial stress response and changes mt dynamics in the heart. (A) Relative mRNA expression levels of mt ATP-dependent proteases and its components in aged (25-month) vs. young (10-month) CBA/CaJ mice hearts, normalized to Gapdh. (B) Relative mRNA expression levels of mt chaperones and Atf5 in aged vs. young hearts normalized to Gapdh. (C) Relative mRNA expression levels of mt dynamic regulators in aged vs. young hearts normalized to Gapdh. Relative expression values were represented as mean ± SEM (n = 3-10). *P < 0.05, **P < 0.01 are considered significant, calculated by an unpaired Student’s t-test using GraphPad Prism software.
