fig1

Turning back time: effects of young plasma on pan epigenetic clocks and implications for the heart

Figure 1. Heterochronic parabiotic treatment of old rats with the extracellular vesicle-enriched fraction of young pig plasma turns back the epigenetic clock in aged rat tissues, and decreases cytokines and oxidative stress. IL-6: Interleukin 6; TNF-α: tumor necrosis factor-alpha; BNP: brain natriuretic peptide; ANF: atrial natriuretic factor; CH: cardiac hypertrophy.

The Journal of Cardiovascular Aging

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https://www.portico.org/publishers/oae/