fig2

Figure 2. (A) Representative ECG tracings showing sinus rhythm (left) and AF (right) after the intracardiac burst atrial burst protocol. (B) Percent of mice in sinus rhythm (blue) and AF (red) in Sham (n = 45) and THOR (n = 86) mice. AF was defined as at least two (out of three) positive AF events after the A-burst protocol. (C) Percent of mice with zero, one, two, and three events after the A-burst protocol in Sham (n = 45) and THOR (n = 86) mice. (D) AF duration in Sham (n = 19) and THOR (n = 46) mice. Only mice with inducible AF episodes are included. Values plotted are equal to the sum of AF duration over the three A-burst protocols. Data are reported as mean ± SEM. P values in panels (B and C) were obtained from chi-square tests. P value in panel (D) was obtained from two-sample Student’s t-tests. *P < 0.05. P ≥ 0.05 denoted ns. ECG: Electrocardiogram; AF: atrial fibrillation; SR: sinus rhythm.