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Figure 10. Myocardial adipogenesis upon suppression or activation of the β-catenin in the postmitotic cardiac myocytes at 4 weeks of age. (A) Representative immunofluorescence images of Perilipin 1 stained thin myocardial sections in the WT, Myh6-Mcm, Myh6-Mcm:Ctnnb1^LoF, and Myh6-Mcm:Ctnnb1^GoF hearts at 4 weeks of age. (B) Quantitative data showing the number of adipocytes in the myocardium following suppression or activation of the cWNT/β-catenin pathway in the postmitotic cardiac myocytes (n = 5). (C) RT-PCR data showing transcript levels of selected genes involved in adipogenesis in the hearts of 4 weeks old WT, Myh6-Mcm, Myh6-Mcm:Ctnnb1^LoF, and Myh6-Mcm:Ctnnb1^GoF mice (n = 4-5). WT: Wild type; Myh6-Mcm: myosin heavy chain 6-MerCreMer; RT-PCR: reverse transcription-polymerase chain reaction.