REFERENCES

1. Pignatti C, D'Adamo S, Stefanelli C, Flamigni F, Cetrullo S. Nutrients and Pathways that Regulate Health Span and Life Span. Geriatrics (Basel) 2020;5:95.

2. Carmona JJ, Michan S. Biology of Healthy Aging and Longevity. Rev Invest Clin 2016;68:7-16.

3. Cummings NE, Lamming DW. Regulation of metabolic health and aging by nutrient-sensitive signaling pathways. Mol Cell Endocrinol 2017;455:13-22.

4. Soultoukis GA, Partridge L. Dietary Protein, Metabolism, and Aging. Annu Rev Biochem 2016;85:5-34.

5. Yu D, Richardson NE, Green CL, et al. The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine. Cell Metab 2021;33:905-922.e6.

6. Richardson NE, Konon EN, Schuster HS, et al. Lifelong restriction of dietary branched-chain amino acids has sex-specific benefits for frailty and lifespan in mice. Nat Aging 2021;1:73-86.

7. Lynch CJ, Adams SH. Branched-chain amino acids in metabolic signalling and insulin resistance. Nat Rev Endocrinol 2014;10:723-36.