REFERENCES

1. Vogt G, Laage R, Shuaib A, Schneider A; VISTA Collaboration. Initial lesion volume is an independent predictor of clinical stroke outcome at day 90: an analysis of the Virtual International Stroke Trials Archive (VISTA) database. Stroke. 2012;43:1266-72.

2. Arsava EM, Helenius J, Avery R, et al. Assessment of the predictive validity of etiologic stroke classification. JAMA Neurol. 2017;74:419-26.

3. Mistry EA, Yeatts SD, Khatri P, et al. National institutes of health stroke scale as an outcome in stroke research: value of ANCOVA over analyzing change from baseline. Stroke. 2022;53:e150-5.

4. Soares Martins T, Trindade D, Vaz M, et al. Diagnostic and therapeutic potential of exosomes in Alzheimer’s disease. J Neurochem. 2021;156:162-81.

5. Eyileten C, Czajka P, Domitrz I, et al. Extracellular vesicle-derived miRNAs in ischemic stroke: roles in neuroprotection, tissue regeneration, and biomarker potential. Cell Mol Neurobiol. 2025;45:31.

6. Wang C, Li Z, Liu Y, Yuan L. Exosomes in atherosclerosis: performers, bystanders, biomarkers, and therapeutic targets. Theranostics. 2021;11:3996-4010.

7. Kita S, Maeda N, Shimomura I. Interorgan communication by exosomes, adipose tissue, and adiponectin in metabolic syndrome. J Clin Invest. 2019;129:4041-9.

8. Salviano-Silva A, Wollmann K, Brenna S, et al. Extracellular vesicles carrying tenascin-c are clinical biomarkers and improve tumor-derived DNA analysis in glioblastoma patients. ACS Nano. 2025;19:9844-59.

9. Wu D, Yan J, Shen X, et al. Profiling surface proteins on individual exosomes using a proximity barcoding assay. Nat Commun. 2019;10:3854.

10. Tran HL, Zheng W, Issadore DA, et al. Extracellular vesicles for clinical diagnostics: from bulk measurements to single-vesicle analysis. ACS Nano. 2025;19:28021-109.

11. Wang Y, Guo S, Zheng J, et al. User testing of the psychometric properties of pictorial-based disability assessment Longshi Scale by healthcare professionals and non-professionals: a Chinese study in Shenzhen. Clin Rehabil. 2019;33:1479-91.

12. Luo J, Cai Y, Xiao P, et al. Inflammation-derived and clinical indicator-based predictive model for ischemic stroke recovery. J Am Heart Assoc. 2024;13:e035609.

13. Butler A, Hoffman P, Smibert P, Papalexi E, Satija R. Integrating single-cell transcriptomic data across different conditions, technologies, and species. Nat Biotechnol. 2018;36:411-20.

14. Hao Y, Hao S, Andersen-Nissen E, et al. Integrated analysis of multimodal single-cell data. Cell. 2021;184:3573-87.e29.

15. Satija R, Farrell JA, Gennert D, Schier AF, Regev A. Spatial reconstruction of single-cell gene expression data. Nat Biotechnol. 2015;33:495-502.

16. Stuart T, Butler A, Hoffman P, et al. Comprehensive integration of single-cell data. Cell. 2019;177:1888-902.e21.

17. Zhang J, Wu J, Wang G, et al. Extracellular vesicles: techniques and biomedical applications related to single vesicle analysis. ACS Nano. 2023;17:17668-98.

18. Hong C, Ndukaife JC. Scalable trapping of single nanosized extracellular vesicles using plasmonics. Nat Commun. 2023;14:4801.

19. Gualerzi A, Niada S, Giannasi C, et al. Raman spectroscopy uncovers biochemical tissue-related features of extracellular vesicles from mesenchymal stromal cells. Sci Rep. 2017;7:9820.

20. Jalali M, Del Real Mata C, Montermini L, et al. MoS2-plasmonic nanocavities for raman spectra of single extracellular vesicles reveal molecular progression in glioblastoma. ACS Nano. 2023;17:12052-71.

21. Welsh JA, Arkesteijn GJA, Bremer M, et al. A compendium of single extracellular vesicle flow cytometry. J Extracell Vesicles. 2023;12:e12299.

22. Rajendran RL, Gangadaran P, Ghosh S, Nagarajan AK, Batabyal R, Ahn BC. Unlocking the secrets of single extracellular vesicles by cutting-edge technologies. Pathol Res Pract. 2025;269:155878.

23. Chen S, Bao Q, Xu W, Zhai X. Extracellular particles: emerging insights into central nervous system diseases. J Nanobiotechnol. 2025;23:263.

24. Eldrup N, Grønholdt ML, Sillesen H, Nordestgaard BG. Elevated matrix metalloproteinase-9 associated with stroke or cardiovascular death in patients with carotid stenosis. Circulation. 2006;114:1847-54.

25. Zhong C, Yang J, Xu T, et al.; CATIS Investigators. Serum matrix metalloproteinase-9 levels and prognosis of acute ischemic stroke. Neurology Neurology. 2017;89:805-12.

26. Guo P, Li H, Zhang X, et al. Matrix metalloproteinase‑9 in hemorrhagic transformation after acute ischemic stroke (Review). Mol Med Rep. 2025;32:225.

27. Sundström J, Evans JC, Benjamin EJ, et al. Relations of plasma matrix metalloproteinase-9 to clinical cardiovascular risk factors and echocardiographic left ventricular measures: the Framingham Heart Study. Circulation. 2004;109:2850-6.

28. Kowalski RG, Ledreux A, Violette JE, et al. Rapid activation of neuroinflammation in stroke: plasma and extracellular vesicles obtained on a mobile stroke unit. Stroke. 2023;54:e52-7.

29. Zhang Y, Wang Y, Wu W, et al. Elevation of neutrophil carcinoembryonic antigen-related cell adhesion molecule 1 associated with multiple inflammatory mediators was related to different clinical stages in ischemic stroke patients. J Clin Lab Anal. 2022;36:e24526.

30. Ji Y, Gao Q, Ma Y, et al. An MMP-9 exclusive neutralizing antibody attenuates blood-brain barrier breakdown in mice with stroke and reduces stroke patient-derived MMP-9 activity. Pharmacol Res. 2023;190:106720.

31. Zhong C, Wang G, Xu T, et al. Tissue inhibitor metalloproteinase-1 and clinical outcomes after acute ischemic stroke. Neurology. 2019;93:819.

32. Liu MB, Wang W, Gao JM, Li F, Shi JS, Gong QH. Icariside II attenuates cerebral ischemia/reperfusion-induced blood-brain barrier dysfunction in rats via regulating the balance of MMP9/TIMP1. Acta Pharmacol Sin. 2020;41:1547-56.

33. Götz L, Rueckschloss U, Ergün S, Kleefeldt F. CEACAM1 in vascular homeostasis and inflammation. Eur J Clin Investig. 2024;54 Suppl 2:e14345.

34. Sobey CG, Drummond GR. CEACAM1: an adhesion molecule that limits blood-brain barrier damage by neutrophils after stroke. Circ Res. 2013;113:952-3.

35. Weiner GM, Ducruet AF. CEACAM1: a novel adhesion molecule that regulates the secretion of matrix metalloproteinase-9 in neutrophils and protects the blood-brain barrier after ischemic stroke. Neurosurgery. 2014;75:N21-2.

36. Ludewig P, Sedlacik J, Gelderblom M, et al. Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits MMP-9-mediated blood-brain-barrier breakdown in a mouse model for ischemic stroke. Circ Res. 2013;113:1013-22.

37. Yu J, Sun G, Chen Y, et al. CEACAM1 inhibited IκB-α/NF-κB signal pathway via targeting MMP-9/TIMP-1 axis in diabetic atherosclerosis. J Cardiovasc Pharmacol. 2020;76:329-36.

38. Uyttenboogaart M, Stewart RE, Vroomen PC, De Keyser J, Luijckx GJ. Optimizing cutoff scores for the Barthel index and the modified Rankin scale for defining outcome in acute stroke trials. Stroke. 2005;36:1984-7.

39. Kim J, Fann DY, Seet RC, Jo DG, Mattson MP, Arumugam TV. Phytochemicals in ischemic stroke. Neuromolecular Med. 2016;18:283-305.

40. Romano JG, Gardener H, Campo-Bustillo I, et al.; MaRISS Investigators*. Predictors of outcomes in patients with mild ischemic stroke symptoms: MaRISS. Stroke. 2021;52:1995-2004.

41. Chung JY, Lee BN, Kim YS, Shin BS, Kang HG. Sex differences and risk factors in recurrent ischemic stroke. Front Neurol. 2023;14:1028431.

42. Rexrode KM, Madsen TE, Yu AYX, Carcel C, Lichtman JH, Miller EC. The impact of sex and gender on stroke. Circ Res. 2022;130:512-28.

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