fig2

Figure 2. The Global Expansion of MISEV from 2014 to 2023. The growing awareness of the need for standardization, transparency, and reproducibility in EV-based research has spread worldwide like a wave. Since the first MISEV guidelines were introduced in 2014, co-authored by 15 researchers, their impact has significantly expanded. The 2018 update was endorsed by 390 authors, while the 2023 edition saw contributions from 72 principal authors and over 1,000 members of the MISEV Consortium. This map illustrates the geographic distribution of MISEV authors from its inception to its most recent update in 2023, reflecting its increasing global adoption. MISEV: Minimum information for studies of extracellular vesicles; EV: extracellular vesicle.