fig3

Figure 3. miR-214 downregulates Xbp1 expression in BMDM. (A) Schematic representation of the IRE1-XBP1 axis and the effects of miR-214; (B) Schematic representation depicting the biological material (BMDM treated with iEVs and TERS CM) analyzed in C; (C) qPCR analysis of Xbp1 in BMDM that were treated with iEVs and TERS CM. Each data point represents an independent experiment with independently-derived BMDM (biological replicates). Data are shown as fold change relative to untreated conditions and normalized using -actin.