fig3
From: Detection by super-resolution microscopy of viral proteins inside bloodborne extracellular vesicles
Figure 3. Comparison of EVs isolated from blood plasma of healthy and Sars-CoV2-infected volunteers. (A) Size and concentration of EVs purified from peripheral blood of healthy and COVID+ patients were determined by NTA; (B and C) Non-permeabilized and permeabilized EVs were immunolabeled for nucleocapsid (blue), CD63 (yellow), and spike (red) and analyzed by dSTORM (B), and then quantified (C); For all EV quantification, a range of 2,000 to 3,000 EV particles were analyzed per replicate per condition. ***: P < 0.001; Scale bars: 100 nm (B).
