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Figure 7. Plasma levels of CD147⁺ sEVs are associated with angiogenesis. (A) Tumor and tumor-adjacent samples were subjected to immunohistochemistry to examine the expression of CD31 (n = 22). Representative images are shown. Scale bar: 100 μm; (B) Correlation between CD31 and CD147 expression in HCC tissues (n = 22); (C) Correlation between CD31 expression in HCC tissues and the ration of plasma CD147⁺ sEVs (n = 22). HCC: hepatocellular carcinoma; CD147⁺ sEVs: CD147-positive small extracellular vesicles.