fig3

Figure 3. Characterization of iPSC-monocyte EVs (mEV). (A) Representative nanoparticle tracking analysis (NTA) showing the majority of mEVs approximately 130nm. (B) Transmission electron microscopy (TEM) of mEVs. Scale bar = 100 nm. (C) mEVs express tetraspanins CD9, CD63 and CD81. (D) Cy-5-labeled mEVs preferentially enter peripheral blood mononuclear cells (PBMC) monocytes over time.