fig3

Figure 3. Comparison of hASC-EV- and hAMSC-EV-embedded miRNA abundance. (A) Principal component analysis of the normalized CRT values of miRNAs. X and Y axes show Principal Components 1 and 2, which explain 77.2% and 11.6% of the total variance, respectively. (B) Heat map of hierarchical clustering analysis of the normalized CRT values of detected miRNAs with sample clustering tree at the top. The color scale of normalized CRT values reflects the absolute expression: red shades indicate high expression levels, while blue shades indicate low expression levels.