fig2

From: An exquisite symphony: protein post-translational modifications govern mitochondrial fate

Figure 2. PTMs on mitochondrial dynamics-related proteins.
We mapped all the PTMs on mitochondrial dynamics-related proteins, and annotated their structural locations. The data source for Figure 2 is generated based on references^{[76,79-87,159]}. The figure was redrawn and designed by the authors based on existing reference images. (A) The PTMs on mitochondrial fisson proteins, and annotated their structural locations; (B) The PTMs on mitochondrial fussion proteins, and annotated their structural locations; (C) The PTMs on mitochondrial mitophagy and transoprt proteins, and annotated their structural locations. Ub: Ubiquitination; SUMO: small ubiquitin-like modifier; Kac: lysine acetylation; P: Phosphorylation; Met: Methylation; Glc: GlcNAc; Suc: Succinylation; Klac: lysine lactylation; PTMs: post-translational modifications; DRP1: dynamin-related protein 1; MID49/51: mitochondrial dynamics proteins of 49 and 51 KDa; MFF: mitochondrial fission factor; FIS1: mitochondrial fission 1 protein; OPA1: optic atrophy 1; MFN1: mitofusins 1; Miro1: mitochondrial Rho GTPase 1; TRAK1: trafficking kinesin-binding protein 1.