fig1

Mechanosensitive apoptosis in Alzheimer′s disease

Figure 1. In microglia, the mechanosensitive PIEZO1 channel responds to stiffness and shear stress by activating, leading to calcium influx. This influx causes membrane hyperpolarization and potassium efflux through KCNN4, promoting inflammasome activation. Created in BioRender. S, G. (2025) https://BioRender.com/9b9433o.

Ageing and Neurodegenerative Diseases
ISSN 2769-5301 (Online)

Portico

All published articles will be preserved here permanently:

https://www.portico.org/publishers/oae/

Portico

All published articles will be preserved here permanently:

https://www.portico.org/publishers/oae/