fig1
Figure 1. In microglia, the mechanosensitive PIEZO1 channel responds to stiffness and shear stress by activating, leading to calcium influx. This influx causes membrane hyperpolarization and potassium efflux through KCNN4, promoting inflammasome activation. Created in BioRender. S, G. (2025) https://BioRender.com/9b9433o.