fig3

Figure 3. Representative optimization outcomes from the ChatGPT Research Group workflow for crystalline porous materials, illustrated here with MOF-321 synthesis. (A) Crystallinity achieved in each experiment across 120 reactions, together with the running average; (B) Representative PXRD patterns from selected experiments; (C) Radar-plot distribution of synthesis parameters for the selected experiments; (D) Mean crystallinity index for the initial random experiments and later optimization iterations grouped into quartiles; (E) Evolution of the synthesis parameters proposed by the Bayesian optimization algorithm as a function of iteration number. Adapted with permission from reference^[14], under CC BY 4.0 license. MOF: Metal-organic framework; PXRD: powder X-ray diffraction.