fig3
Figure 3. Cardiac EC subpopulations identified by scRNA-seq. Cardiac ECs represent a heterogeneous population that can be subdivided into several functionally distinct groups using scRNA-seq based on their specific cell markers. Traditional vascular EC subtypes include arterial, venous, capillary, and lymphatic ECs[58-60]. Recent studies in DCM have also revealed novel EC subtypes that play important roles in disease progression, such as lipid metabolism-associated ECs, angiogenic ECs, and pro-inflammatory ECs[14,23,62].
