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Figure 1. Workflow for Omics Biomarker Discovery. A flowchart illustrates the step-by-step process of omics-based novel biomarker search in ischemic stroke. 1. Biospecimen Collection: Samples are collected from human beings or animals. Time of collection and quality are essential. 2. Omics Analysis: High-throughput processes such as genomics, transcriptomics, proteomics, and metabolomics are employed. Large volumes of gene expression information, protein expression, metabolite changes, and regulatory RNA patterns are generated. 3. Bioinformatics and artificial intelligence: Machine learning, pattern recognition, and network analysis algorithms for target identification and reduction of false positives. 4. Validation and Application: Validation with independent large clinical cohorts.