fig3
Figure 3. Functions and mechanisms of snoRNAs in cardiovascular diseases. CVD: Cardiovascular disease; TOF: tetralogy of fallot; DCM: dilated cardiomyopathy; HCM: hypertrophic cardiomyopathy; AS: atherosclerosis; CHD: coronary heart disease; MI: myocardial infarction; HF: heart failure; AF: atrial fibrillation; PAD: peripheral artery disease; VR: vascular remodeling; PXDN: peroxidasin; gata4: gata binding protein 4; mbnl1: muscleblind like splicing regulator 1; Tjp1: tight junction protein 1; Map3k7: mitogen-activated protein kinase kinase kinase 7; Sppl2a: signal peptide peptidase like 2A; NOX1: NADPH oxidase 1; RBC: red blood cell; C3a: complement component 3a; hiPSC-CMs: human induced pluripotent stem cell-derived cardiomyocytes; TGF-β: transforming growth factor beta; CBSC-dEXO: cortical bone stem cell-derived exosomes; DE: differential expression; RPL13A: ribosomal protein L13a; tRNALeu: tRNA to protect the leucine anticodon TAA. c.ACTC1: actin alpha cardiac muscle 1. (Created in BioRender. Cao, H. (2026) https://BioRender.com/acu5pfs).






