fig1
From: Emerging roles and mechanisms of small nucleolar RNA in cardiovascular diseases: research progress
Figure 1. Schematic of snoRNA structure and snoRNP assembly. (A) snoRNA structural features. (B) snoRNP assembly. The C/D box snoRNP is composed of a snoRNA bound to four core proteins—SNU13, NOP58, NOP56, and Fibrillarin—and catalyzes site-specific 2'-O-ribose methylation of target RNAs through its antisense element. The H/ACA box snoRNP consists of a snoRNA associated with the four core proteins GAR1, NOP10, NHP2, and Dyskerin, and facilitates pseudouridylation of target RNAs via its pseudouridylation pocket. (Created in BioRender. Cao, H. (2026) https://BioRender.com/o1aj8wx).
