fig1
From: Stem cell-based strategies for vascular aging: from mechanistic insights to clinical translation
Figure 1. Schematic of the regulatory network driving stem cell pathological aging. Multiple factors, including Oxidative Stress, Gut Microbiota Dysbiosis, Inflammatory Microenvironment, ECM Remodeling, RAS System Imbalance, Thrombus Formation, Hemodynamic Changes, and Epigenetic Changes, promote stem cell pathological aging (solid arrows denote inducing effects). ECM: Extracellular matrix; RAS: renin-angiotensin system. (By Figdraw, ID: YASWOe3f11).
