REFERENCES
1. Fagiani F, Di Marino D, Romagnoli A, et al. Molecular regulations of circadian rhythm and implications for physiology and diseases. Signal Transduct Target Ther 2022;7:41.
2. Breitenbach T, Helfrich-Förster C, Dandekar T. An effective model of endogenous clocks and external stimuli determining ciradian rhythms. 2021.
3. Ferrell JM. Circadian rhythms and inflammatory diseases of the liver and gut. Liver Research 2023;7:196-206.
5. Balsalobre A, Damiola F, Schibler U. A serum shock induces circadian gene expression in mammalian tissue culture cells. Cell 1998;93:929-37.
6. Ko CH, Takahashi JS. Molecular components of the mammalian circadian clock. Hum Mol Genet 2006;15 Spec No 2:R271-7.
7. Reppert SM, Weaver DR. Molecular analysis of mammalian circadian rhythms. Annu Rev Physiol 2001;63:647-76.
8. Gekakis N, Staknis D, Nguyen HB, et al. Role of the CLOCK protein in the mammalian circadian mechanism. Science 1998;280:1564-9.
9. Kume K, Zylka MJ, Sriram S, et al. mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop. Cell 1999;98:193-205.
10. Zheng B, Albrecht U, Kaasik K, et al. Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock. Cell 2001;105:683-94.
11. Takahashi JS. Transcriptional architecture of the mammalian circadian clock. Nat Rev Genet 2017;18:164-79.
12. Buhr ED, Takahashi JS. Molecular components of the mammalian circadian clock. Handb Exp Pharmacol 2013;217:3-27.
13. Mohawk JA, Green CB, Takahashi JS. Central and peripheral circadian clocks in mammals. Annu Rev Neurosci 2012;35:445-62.
14. Mason IC, Qian J, Adler GK, Scheer FAJL. Impact of circadian disruption on glucose metabolism: implications for type 2 diabetes. Diabetologia 2020;63:462-72.
15. Chaput JP, McHill AW, Cox RC, et al. The role of insufficient sleep and circadian misalignment in obesity. Nat Rev Endocrinol 2023;19:82-97.
16. Pariollaud M, Lamia KA. Cancer in the fourth dimension: what is the impact of circadian disruption? Cancer Discov 2020;10:1455-64.
17. Straif K, Baan R, Grosse Y, et al. WHO International Agency For Research on Cancer Monograph Working Group. Carcinogenicity of shift-work, painting, and fire-fighting. Lancet Oncol 2007;8:1065-6.
18. Finger AM, Kramer A. Mammalian circadian systems: organization and modern life challenges. Acta Physiol (Oxf) 2021;231:e13548.
19. Boivin DB, Boudreau P, Kosmadopoulos A. Disturbance of the circadian system in shift work and its health impact. J Biol Rhythms 2022;37:3-28.
20. Morris CJ, Yang JN, Garcia JI, et al. Endogenous circadian system and circadian misalignment impact glucose tolerance via separate mechanisms in humans. Proc Natl Acad Sci U S A 2015;112:E2225-34.
21. Cuesta M, Boudreau P, Dubeau-Laramée G, Cermakian N, Boivin DB. Simulated night shift disrupts circadian rhythms of immune functions in humans. J Immunol 2016;196:2466-75.
22. Bescos R, Boden MJ, Jackson ML, et al. Four days of simulated shift work reduces insulin sensitivity in humans. Acta Physiol (Oxf) 2018;223:e13039.
23. Wefers J, van Moorsel D, Hansen J, et al. Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle. Proc Natl Acad Sci U S A 2018;115:7789-94.
24. Ruiz FS, Rosa DS, Zimberg IZ, et al. Night shift work and immune response to the meningococcal conjugate vaccine in healthy workers: a proof of concept study. Sleep Med 2020;75:263-75.
25. Kervezee L, Koshy A, Cermakian N, Boivin DB. The effect of night shifts on 24-h rhythms in the urinary metabolome of police officers on a rotating work schedule. J Biol Rhythms 2023;38:64-76.
26. Hattammaru M, Tahara Y, Kikuchi T, et al. The effect of night shift work on the expression of clock genes in beard hair follicle cells. Sleep Med 2019;56:164-70.
27. Yang Z, Black K, Ohman-Strickland P, et al. Disruption of central and peripheral circadian clocks and circadian controlled estrogen receptor rhythms in night shift nurses in working environments. FASEB J 2024;38:e23719.
28. Reszka E, Przybek M, Muurlink O, Pepłonska B. Circadian gene variants and breast cancer. Cancer Lett 2017;390:137-45.
29. Koshy A, Cuesta M, Boudreau P, Cermakian N, Boivin DB. Disruption of central and peripheral circadian clocks in police officers working at night. FASEB J 2019;33:6789-800.
30. Cuesta M, Boudreau P, Cermakian N, Boivin DB. Rapid resetting of human peripheral clocks by phototherapy during simulated night shift work. Sci Rep 2017;7:16310.
31. Resuehr D, Wu G, Johnson RL Jr, Young ME, Hogenesch JB, Gamble KL. Shift work disrupts circadian regulation of the transcriptome in hospital nurses. J Biol Rhythms 2019;34:167-77.
32. Pham TT, Lee ES, Kong SY, et al. Night-shift work, circadian and melatonin pathway related genes and their interaction on breast cancer risk: evidence from a case-control study in Korean women. Sci Rep 2019;9:10982.
33. Mukherji A, Bailey SM, Staels B, Baumert TF. The circadian clock and liver function in health and disease. J Hepatol 2019;71:200-11.
34. Watanabe K, Sakuraya A, Kawakami N, et al. Work-related psychosocial factors and metabolic syndrome onset among workers: a systematic review and meta-analysis. Obes Rev 2018;19:1557-68.
35. Sun M, Feng W, Wang F, et al. Meta-analysis on shift work and risks of specific obesity types. Obes Rev 2018;19:28-40.
36. Vetter C, Dashti HS, Lane JM, et al. Night shift work, genetic risk, and type 2 diabetes in the UK biobank. Diabetes Care 2018;41:762-9.
37. Zhang S, Wang Y, Zhu Y, Li X, Song Y, Yuan J. Rotating night shift work, exposure to light at night, and glomerular filtration rate: baseline results from a Chinese occupational cohort. Int J Environ Res Public Health 2020;17:9035.
38. VoPham T, Weaver MD, Vetter C, et al. Circadian misalignment and hepatocellular carcinoma incidence in the United States. Cancer Epidemiol Biomarkers Prev 2018;27:719-27.
39. Kettner NM, Voicu H, Finegold MJ, et al. Circadian homeostasis of liver metabolism suppresses hepatocarcinogenesis. Cancer Cell 2016;30:909-24.
40. Balakrishnan M, El-Serag HB, Kanwal F, Thrift AP. Shiftwork is not associated with increased risk of NAFLD: findings from the National Health and Nutrition Examination Survey. Dig Dis Sci 2017;62:526-33.
41. Wang F, Zhang L, Wu S, et al. Night shift work and abnormal liver function: is non-alcohol fatty liver a necessary mediator? Occup Environ Med 2019;76:83-9.
42. Song E, Kim JA, Roh E, et al. Long working hours and risk of nonalcoholic fatty liver disease: Korea National Health and Nutrition Examination Survey VII. Front Endocrinol (Lausanne) 2021;12:647459.
43. Blask DE, Dauchy RT, Sauer LA, Krause JA, Brainard GC. Light during darkness, melatonin suppression and cancer progression. Neuro Endocrinol Lett 2002;23 Suppl 2:52-6.
44. Touitou Y, Point S. Effects and mechanisms of action of light-emitting diodes on the human retina and internal clock. Environ Res 2020;190:109942.
45. Wang H, Gu Y, Zheng L, et al. Association between bedtime and the prevalence of newly diagnosed non-alcoholic fatty liver disease in adults. Liver Int 2018;38:2277-86.
46. West AC, Smith L, Ray DW, Loudon ASI, Brown TM, Bechtold DA. Misalignment with the external light environment drives metabolic and cardiac dysfunction. Nat Commun 2017;8:417.
48. Garcia-Saenz A, Sánchez de Miguel A, Espinosa A, et al. Evaluating the association between artificial light-at-night exposure and breast and prostate cancer risk in Spain (MCC-Spain Study). Environ Health Perspect 2018;126:047011.
49. Guo Y, Liu Y, Huang X, et al. The effects of shift work on sleeping quality, hypertension and diabetes in retired workers. PLoS One 2013;8:e71107.
50. Vetter C, Devore EE, Wegrzyn LR, et al. Association between rotating night shift work and risk of coronary heart disease among women. JAMA 2016;315:1726-34.
51. Sun M, Feng W, Wang F, et al. Night shift work exposure profile and obesity: baseline results from a Chinese night shift worker cohort. PLoS One 2018;13:e0196989.
52. Zhang S, Wang Y, Wang Z, et al. Rotating night shift work and non-alcoholic fatty liver disease among steelworkers in China: a cross-sectional survey. Occup Environ Med 2020;77:333-9.
53. Streng AA, Loef B, Dollé MET, et al. Night shift work characteristics are associated with several elevated metabolic risk factors and immune cell counts in a cross-sectional study. Sci Rep 2022;12:2022.
54. Anjum B, Verma NS, Tiwari S, et al. Association of salivary cortisol with chronomics of 24 hours ambulatory blood pressure/heart rate among night shift workers. Biosci Trends 2011;5:182-8.
55. Adan A, Archer SN, Hidalgo MP, Di Milia L, Natale V, Randler C. Circadian typology: a comprehensive review. Chronobiol Int 2012;29:1153-75.
56. Behren J, Hurley S, Goldberg D, Clague DeHart J, Wang SS, Reynolds P. Chronotype and risk of post-menopausal endometrial cancer in the California teachers study. Chronobiol Int 2021;38:1151-61.
57. Maidstone R, Rutter MK, Marjot T, Ray DW, Baxter M. Shift work and evening chronotype are related to prevalent non-alcoholic fatty liver disease in 282,303 UK biobank participants. medRxiv ;. 2022:2022-05.
58. Adamovich Y, Rousso-Noori L, Zwighaft Z, et al. Circadian clocks and feeding time regulate the oscillations and levels of hepatic triglycerides. Cell Metab 2014;19:319-30.
59. Vetrani C, Barrea L, Verde L, et al. Evening chronotype is associated with severe NAFLD in obesity. Int J Obes (Lond) 2022;46:1638-43.
60. Weng Z, Ou W, Huang J, et al. Circadian misalignment rather than sleep duration is associated with MAFLD: a population-based propensity score-matched study. Nat Sci Sleep 2021;13:103-11.
61. Perez-Diaz-del-Campo N, Castelnuovo G, Caviglia GP, et al. Role of circadian clock on the pathogenesis and lifestyle management in non-alcoholic fatty liver disease. Nutrients 2022;14:5053.
62. Wittmann M, Dinich J, Merrow M, Roenneberg T. Social jetlag: misalignment of biological and social time. Chronobiol Int 2006;23:497-509.
63. Caliandro R, Streng AA, van Kerkhof LWM, van der Horst GTJ, Chaves I. Social Jetlag and related risks for human health: a timely review. Nutrients 2021;13:4543.
64. Suikki T, Maukonen M, Partonen T, Jousilahti P, Kanerva N, Männistö S. Association between social jet lag, quality of diet and obesity by diurnal preference in Finnish adult population. Chronobiol Int 2021;38:720-31.
65. Islam Z, Akter S, Kochi T, et al. Association of social jetlag with metabolic syndrome among Japanese working population: the Furukawa Nutrition and Health Study. Sleep Med 2018;51:53-8.
66. Koopman ADM, Rauh SP, van 't Riet E, et al. The association between social Jetlag, the metabolic syndrome, and type 2 diabetes mellitus in the general population: the new hoorn study. J Biol Rhythms 2017;32:359-68.
67. Anothaisintawee T, Lertrattananon D, Thamakaison S, Thakkinstian A, Reutrakul S. The relationship among morningness-eveningness, sleep duration, social Jetlag, and body mass index in asian patients with prediabetes. Front Endocrinol (Lausanne) 2018;9:435.
68. Kant AK, Graubard BI. 40-year trends in meal and snack eating behaviors of American adults. J Acad Nutr Diet 2015;115:50-63.
69. Esteban JP, Rein L, Szabo A, Gawrieh S, Saeian K. Not just what, but also when you eat: analyzing the impact of meal timing patterns on non-alcoholic fatty liver disease. Hepatology 2016;64:S17A. Available from: https://www.researchgate.net/publication/331977419_Not_just_what_but_also_when_you_eat_Analyzing_the_impact_of_meal_timing_patterns_on_non-alcoholic_fatty_liver_disease. [Last accessed on 28 Oct 2024].
70. Leech RM, Timperio A, Livingstone KM, Worsley A, McNaughton SA. Temporal eating patterns: associations with nutrient intakes, diet quality, and measures of adiposity. Am J Clin Nutr 2017;106:1121-30.
71. Miyake T, Kumagi T, Hirooka M, et al. Significance of exercise in nonalcoholic fatty liver disease in men: a community-based large cross-sectional study. J Gastroenterol 2015;50:230-7.
72. Pot GK. Sleep and dietary habits in the urban environment: the role of chrono-nutrition. Proc Nutr Soc 2018;77:189-98.
73. Yin C, Li Z, Xiang Y, et al. Effect of intermittent fasting on non-alcoholic fatty liver disease: systematic review and meta-analysis. Front Nutr 2021;8:709683.
74. Grant CL, Coates AM, Dorrian J, et al. Timing of food intake during simulated night shift impacts glucose metabolism: a controlled study. Chronobiol Int 2017;34:1003-13.
75. Liu C, Zhong R, Lou J, et al. Nighttime sleep duration and risk of nonalcoholic fatty liver disease: the Dongfeng-Tongji prospective study. Ann Med 2016;48:468-76.
76. Shigiyama F, Kumashiro N, Tsuneoka Y, et al. Mechanisms of sleep deprivation-induced hepatic steatosis and insulin resistance in mice. Am J Physiol Endocrinol Metab 2018;315:E848-58.
77. Kim D, Kim HJ, Kushida CA, Heo NY, Ahmed A, Kim WR. Short sleep duration is associated with abnormal serum aminotransferase activities and nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol 2018;16:588-90.
78. Kim CW, Yun KE, Jung HS, et al. Sleep duration and quality in relation to non-alcoholic fatty liver disease in middle-aged workers and their spouses. J Hepatol 2013;59:351-7.
79. Cordina-Duverger E, Uchai S, Tvardik N, et al. Sleep traits, night shift work and lung cancer risk among women: results from a population-based case-control study in France (The WELCA Study). Int J Environ Res Public Health 2022;19:16246.
80. White AJ, Weinberg CR, Park YM, et al. Sleep characteristics, light at night and breast cancer risk in a prospective cohort. Int J Cancer 2017;141:2204-14.
81. Kecklund G, Axelsson J. Health consequences of shift work and insufficient sleep. BMJ 2016;355:i5210.
82. Hemmer A, Mareschal J, Dibner C, et al. The effects of shift work on cardio-metabolic diseases and eating patterns. Nutrients 2021;13:4178.
83. Tanaka R, Tsuji M, Kusuhara K, Kawamoto T. Japan Environment and Children’s Study Group. Association between time-related work factors and dietary behaviors: results from the Japan Environment and Children’s Study (JECS). Environ Health Prev Med 2018;23:62.
84. Meng R, Wang H, Si Z, et al. Analysis of factors affecting nonalcoholic fatty liver disease in Chinese steel workers and risk assessment studies. Lipids Health Dis 2023;22:123.
85. Lin YC, Chen PC. Persistent rotating shift work exposure is a tough second hit contributing to abnormal liver function among on-site workers having sonographic fatty liver. Asia Pac J Public Health 2015;27:NP1765-74.
86. Lin YC, Hsieh IC, Chen PC. Long-term day-and-night rotating shift work poses a barrier to the normalization of alanine transaminase. Chronobiol Int 2014;31:487-95.
87. Tse LA, Wang F, Zhang L, Li Z. O4A.5 Night shift work is associated with abnormal liver function. Occup Environ Med 2019;76:A33.2-A33.
88. Ferrell JM, Chiang JY. Circadian rhythms in liver metabolism and disease. Acta Pharm Sin B 2015;5:113-22.
89. Jacobi D, Liu S, Burkewitz K, et al. Hepatic bmal1 regulates rhythmic mitochondrial dynamics and promotes metabolic fitness. Cell Metab 2015;22:709-20.
90. Saran AR, Dave S, Zarrinpar A. Circadian rhythms in the pathogenesis and treatment of fatty liver disease. Gastroenterology 2020;158:1948-1966.e1.
91. Downton P, Sanna F, Maidstone R, et al. Chronic inflammatory arthritis drives systemic changes in circadian energy metabolism. Proc Natl Acad Sci U S A 2022;119:e2112781119.
92. Koike N, Yoo SH, Huang HC, et al. Transcriptional architecture and chromatin landscape of the core circadian clock in mammals. Science 2012;338:349-54.
93. Daniels LJ, Kay D, Marjot T, Hodson L, Ray DW. Circadian regulation of liver metabolism: experimental approaches in human, rodent, and cellular models. Am J Physiol Cell Physiol 2023;325:C1158-77.
94. Yeung CHC, Bauer C, Xiao Q. Associations between rest-activity rhythms and liver function tests: the US national health and nutrition examination survey, 2011-2014. Clocks Sleep 2023;5:667-85.
95. Shi D, Chen J, Wang J, et al. Circadian clock genes in the metabolism of non-alcoholic fatty liver disease. Front Physiol 2019;10:423.
96. Le Martelot G, Claudel T, Gatfield D, et al. REV-ERBalpha participates in circadian SREBP signaling and bile acid homeostasis. PLoS Biol 2009;7:e1000181.
97. Kim K, Lee YJ, Kwon SC, et al. Correlation between shift work and non-alcoholic fatty liver disease among male workers in the steel manufacturing company of Korea: a cross-sectional study. Ann Occup Environ Med 2022;34:e33.
100. Reinke H, Asher G. Crosstalk between metabolism and circadian clocks. Nat Rev Mol Cell Biol 2019;20:227-41.
101. Reinke H, Asher G. Circadian clock control of liver metabolic functions. Gastroenterology 2016;150:574-80.
102. Lamia KA, Papp SJ, Yu RT, et al. Cryptochromes mediate rhythmic repression of the glucocorticoid receptor. Nature 2011;480:552-6.
103. Xiong X, Lin Y, Lee J, et al. Chronic circadian shift leads to adipose tissue inflammation and fibrosis. Mol Cell Endocrinol 2021;521:111110.
104. Nagaya T, Yoshida H, Takahashi H, Kawai M. Markers of insulin resistance in day and shift workers aged 30-59 years. Int Arch Occup Environ Health 2002;75:562-8.
105. Eckel-Mahan KL, Patel VR, de Mateo S, et al. Reprogramming of the circadian clock by nutritional challenge. Cell 2013;155:1464-78.
106. Chavan R, Feillet C, Costa SS, et al. Liver-derived ketone bodies are necessary for food anticipation. Nat Commun 2016;7:10580.
107. Yang X, Downes M, Yu RT, et al. Nuclear receptor expression links the circadian clock to metabolism. Cell 2006;126:801-10.
108. Salgado-Delgado R, Angeles-Castellanos M, Saderi N, Buijs RM, Escobar C. Food intake during the normal activity phase prevents obesity and circadian desynchrony in a rat model of night work. Endocrinology 2010;151:1019-29.
109. Marti AR, Meerlo P, Grønli J, et al. Shift in food intake and changes in metabolic regulation and gene expression during simulated night-shift work: a rat model. Nutrients 2016;8:712.
110. Hatori M, Vollmers C, Zarrinpar A, et al. Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet. Cell Metab 2012;15:848-60.
111. Romero-Gómez M, Zelber-Sagi S, Trenell M. Treatment of NAFLD with diet, physical activity and exercise. J Hepatol 2017;67:829-46.
112. Samhat Z, Attieh R, Sacre Y. Relationship between night shift work, eating habits and BMI among nurses in Lebanon. BMC Nurs 2020;19:25.
113. Buchvold HV, Pallesen S, Øyane NM, Bjorvatn B. Associations between night work and BMI, alcohol, smoking, caffeine and exercise--a cross-sectional study. BMC Public Health 2015;15:1112.
114. Kim MJ, Son KH, Park HY, et al. Association between shift work and obesity among female nurses: Korean Nurses’ Survey. BMC Public Health 2013;13:1204.
115. Buchvold HV, Pallesen S, Waage S, Bjorvatn B. Shift work schedule and night work load: effects on body mass index - a four-year longitudinal study. Scand J Work Environ Health 2018;44:251-7.
116. Milić S, Lulić D, Štimac D. Non-alcoholic fatty liver disease and obesity: biochemical, metabolic and clinical presentations. World J Gastroenterol 2014;20:9330-7.
117. Okamura T, Hashimoto Y, Hamaguchi M, Obora A, Kojima T, Fukui M. Short sleep duration is a risk of incident nonalcoholic fatty liver disease: a population-based longitudinal study. J Gastrointestin Liver Dis 2019;28:73-81.
118. Kim SM, Neuendorff N, Alaniz RC, Sun Y, Chapkin RS, Earnest DJ. Shift work cycle-induced alterations of circadian rhythms potentiate the effects of high-fat diet on inflammation and metabolism. FASEB J 2018;32:3085-95.
119. Christie S, Vincent AD, Li H, et al. A rotating light cycle promotes weight gain and hepatic lipid storage in mice. Am J Physiol Gastrointest Liver Physiol 2018;315:G932-42.
120. Yue F, Xia K, Wei L, et al. Effects of constant light exposure on sphingolipidomics and progression of NASH in high-fat-fed rats. J Gastroenterol Hepatol 2020;35:1978-89.
121. Che Y, Tang R, Zhang H, et al. Development of a prediction model for predicting the prevalence of nonalcoholic fatty liver disease in Chinese nurses: the first-year follow data of a web-based ambispective cohort study. BMC Gastroenterol 2024;24:72.
122. Eslam M, Newsome PN, Sarin SK, et al. A new definition for metabolic dysfunction-associated fatty liver disease: an international expert consensus statement. J Hepatol 2020;73:202-9.
123. Boccatonda A, Andreetto L, D'Ardes D, et al. From NAFLD to MAFLD: definition, pathophysiological basis and cardiovascular implications. Biomedicines 2023;11:883.
124. Guo X, Yin X, Liu Z, Wang J. Non-alcoholic fatty liver disease (NAFLD) pathogenesis and natural products for prevention and treatment. Int J Mol Sci 2022;23:15489.
125. Shetty A, Hsu JW, Manka PP, Syn WK. Role of the Circadian clock in the metabolic syndrome and nonalcoholic fatty liver disease. Dig Dis Sci 2018;63:3187-206.
126. Tahara Y, Shibata S. Circadian rhythms of liver physiology and disease: experimental and clinical evidence. Nat Rev Gastroenterol Hepatol 2016;13:217-26.
127. Rivera-Coll A, Fuentes-Arderiu X, Díez-Noguera A. Circadian rhythms of serum concentrations of 12 enzymes of clinical interest. Chronobiol Int 1993;10:190-200.
128. Padilla J, Osman NM, Bissig-Choisat B, et al. Circadian dysfunction induces NAFLD-related human liver cancer in a mouse model. J Hepatol 2024;80:282-92. [PMID: 37890720].
129. Steensels S, Qiao J, Ersoy BA. Transcriptional regulation in non-alcoholic fatty liver disease. Metabolites 2020;10:283.
131. Lee S, Donehower LA, Herron AJ, Moore DD, Fu L. Disrupting circadian homeostasis of sympathetic signaling promotes tumor development in mice. PLoS One 2010;5:e10995.
132. Fleet T, Stashi E, Zhu B, et al. Genetic and environmental models of circadian disruption link SRC-2 function to hepatic pathology. J Biol Rhythms 2016;31:443-60.
133. Iwamoto A, Kawai M, Furuse M, Yasuo S. Effects of chronic jet lag on the central and peripheral circadian clocks in CBA/N mice. Chronobiol Int 2014;31:189-98.
134. Xu J, Ni S, Wang Y, et al. Shift work and nonalcoholic fatty liver disease incidence among Chinese rail workers: a 4-year longitudinal cohort study. Int Arch Occup Environ Health 2023;96:179-90.
135. Choi H, Oh HJ, Shin JS, et al. Relationship between shift work and liver enzymes: a cross-sectional study based on the Korea National Health and Examination Survey (2007-2015). Ann Occup Environ Med 2019;31:e15.
136. Hung W-C, Yu T-H, Wu C-C, et al. Nonalcoholic fatty liver disease is related to abnormal corrected QT interval and left ventricular hypertrophy in Chinese male steelworkers. Int J Environ Res Public Health 2022;19:14555.
137. Mozos I, Filimon L. QT and Tpeak-Tend intervals in shift workers. J Electrocardiol 2013;46:60-5.
138. Lecca LI, Portoghese I, Mucci N, et al. Association between work-related stress and QT prolongation in male workers. Int J Environ Res Public Health 2019;16:4781.
139. Li Q, Zhang S, Yu M, et al. Rotating night shift work and liver enzymes-associated abnormalities among steelworkers: a cross-sectional study from a Chinese cohort. Int Arch Occup Environ Health 2022;95:1935-44.
140. Taechasan N, Jiamjarasrangsi W. Relationship of shift work with liver enzyme abnormalities and nonalcoholic fatty liver disease: a retrospective cohort study of Thai workers in Bangkok, Thailand. J Public Hlth Dev 2024;22:126-44.
141. Maidstone R, Rutter MK, Marjot T, Ray DW, Baxter M. Shift work and evening chronotype are associated with hepatic fat fraction and non-alcoholic fatty liver disease in 282,303 UK biobank participants. Endocr Connect 2024;13:e230472.
142. Chatur DK, Pati SK, Ghate JR, Nanda R, Sinha M, Kodapi K. Nonalcoholic fatty liver disease in shift workers and its effect on peripheral nerve conduction: a cross-sectional study. Cureus 2024;16:e60632.
143. Nakamura K, Motohashi Y, Kikuchi S, Tanaka M, Nakano S. Liver transferase activity in healthy Japanese employees aged 18-39 years. Ind Health 1998;36:218-22.
144. Khosravipour M, Shah Mohammadi M. The effects of exposure to night shift work on liver function: a cross-sectional study with emphasis of alkaline phosphatase enzyme. Chronobiol Int 2020;37:142-5.
145. Lin YC, Hsiao TJ, Chen PC. Shift work aggravates metabolic syndrome development among early-middle-aged males with elevated ALT. World J Gastroenterol 2009;15:5654-61.
146. Sun Z, Li L, Yan Z, et al. Circadian rhythm disorders elevate macrophages cytokines release and promote multiple tissues/organs dysfunction in mice. Physiol Behav 2022;249:113772.
147. Charles LE, Gu JK, Fekedulegn D, Andrew ME, Violanti JM, Burchfiel CM. Association between shiftwork and glomerular filtration rate in police officers. J Occup Environ Med 2013;55:1323-8.
148. Koritala BSC, Dakup PP, Porter KI, Gaddameedhi S. The impact of shift-work light conditions on tissue-specific circadian rhythms of canonical clock genes: insights from a mouse model study. F1000Res 2023;12:762.
149. Yoshimura M, Flynn BP, Kershaw YM, et al. Phase-shifting the circadian glucocorticoid profile induces disordered feeding behaviour by dysregulating hypothalamic neuropeptide gene expression. Commun Biol 2023;6:998.
150. Michelotti GA, Machado MV, Diehl AM. NAFLD, NASH and liver cancer. Nat Rev Gastroenterol Hepatol 2013;10:656-65.
151. Zhao Y, Lu X, Wang Y, et al. Peripheral blood lipid and liver and kidney function test results in long-term night shift nurses: a cross-sectional study in South China. Front Endocrinol (Lausanne) 2023;14:1237467.
152. Virtanen M, Heikkilä K, Jokela M, et al. Long working hours and coronary heart disease: a systematic review and meta-analysis. Am J Epidemiol 2012;176:586-96.
153. Kivimäki M, Jokela M, Nyberg ST, et al. IPD-Work Consortium. Long working hours and risk of coronary heart disease and stroke: a systematic review and meta-analysis of published and unpublished data for 603,838 individuals. Lancet 2015;386:1739-46.
154. Kivimäki M, Virtanen M, Kawachi I, et al. Long working hours, socioeconomic status, and the risk of incident type 2 diabetes: a meta-analysis of published and unpublished data from 222 120 individuals. Lancet Diabetes Endocrinol 2015;3:27-34.
155. Kobayashi T, Suzuki E, Takao S, Doi H. Long working hours and metabolic syndrome among Japanese men: a cross-sectional study. BMC Public Health 2012;12:395.
156. Kim BM, Lee BE, Park HS, et al. Long working hours and overweight and obesity in working adults. Ann Occup Environ Med 2016;28:36.
157. Park H, Lee SJ. Working hours and nonalcoholic fatty liver disease according to sleep duration. Chronobiol Int 2019;36:1671-80.
158. Lee Y, Mun E, Park S, Lee W. Long working hours are associated with a higher risk of non-alcoholic fatty liver disease: a large population-based Korean cohort study. PLoS One 2021;16:e0255118.
159. Lee K, Suh C, Kim J-E, Park JO. The impact of long working hours on psychosocial stress response among white-collar workers. Ind Health 2017;55:46-53.
160. Li C, Guo P, Okekunle AP, et al. Lean non-alcoholic fatty liver disease patients had comparable total caloric, carbohydrate, protein, fat, iron, sleep duration and overtime work as obese non-alcoholic fatty liver disease patients. J Gastroenterol Hepatol 2019;34:256-62.
161. Lim GY, Chang Y, Kim I, Ryu S, Kwon R, Song J. Long working hours and increased risks of lean non-alcoholic fatty liver disease among Korean men and women. Sci Rep 2023;13:12230.
162. Huang H, Liu Z, Xie J, Xu C. Association between night shift work and NAFLD: a prospective analysis of 281,280 UK Biobank participants. BMC Public Health 2023;23:1282.
163. McHenry S, Park Y, Davidson NO. Validation of the dallas steatosis index to predict nonalcoholic fatty liver disease in the UK Biobank population. Clin Gastroenterol Hepatol 2022;20:2638-40.
164. Yki-Järvinen H. Non-alcoholic fatty liver disease as a cause and a consequence of metabolic syndrome. Lancet Diabetes Endocrinol 2014;2:901-10.
165. Kim C, Cho Y. Working conditions and leisure-time physical activity among waged workers in South Korea: a cross-sectional study. J Occup Health 2015;57:259-67.
167. Siegel AB, Zhu AX. Metabolic syndrome and hepatocellular carcinoma: two growing epidemics with a potential link. Cancer 2009;115:5651-61.
168. Gu F, Xu S, Devesa SS, et al. Longitude position in a time zone and cancer risk in the United States. Cancer Epidemiol Biomarkers Prev 2017;26:1306-11.
169. Liang Y, Wang S, Huang X, et al. Dysregulation of Circadian clock genes as significant clinic factor in the tumorigenesis of hepatocellular carcinoma. Comput Math Methods Med 2021;2021:8238833.
171. Arafa A, Eshak ES, Iso H, Muraki I, Tamakoshi A. Night work, rotating shift work, and the risk of cancer in Japanese men and women: the JACC study. J Epidemiol 2021;31:585-92.
172. Kubo T, Oyama I, Nakamura T, et al. Industry-based retrospective cohort study of the risk of prostate cancer among rotating-shift workers. Int J Urol 2011;18:206-11.
173. Koppes LL, Geuskens GA, Pronk A, Vermeulen RC, de Vroome EM. Night work and breast cancer risk in a general population prospective cohort study in The Netherlands. Eur J Epidemiol 2014;29:577-84.
174. Wegrzyn LR, Tamimi RM, Rosner BA, et al. Rotating night-shift work and the risk of breast cancer in the nurses’ health studies. Am J Epidemiol 2017;186:532-40.
175. Jones ME, Schoemaker MJ, McFadden EC, Wright LB, Johns LE, Swerdlow AJ. Night shift work and risk of breast cancer in women: the Generations Study cohort. Br J Cancer 2019;121:172-9.
176. Kwon P, Lundin J, Li W, et al. Night shift work and lung cancer risk among female textile workers in Shanghai, China. J Occup Environ Hyg 2015;12:334-41.
177. Schernhammer ES, Feskanich D, Liang G, Han J. Rotating night-shift work and lung cancer risk among female nurses in the United States. Am J Epidemiol 2013;178:1434-41.
178. Haghayegh S, Liu Y, Zhang Y, et al. Rotating night shift work and bladder cancer risk in women: results of two prospective cohort studies. Int J Environ Res Public Health 2023;20:2202.
179. Lin Y, Nishiyama T, Kurosawa M, et al. JACC Study Group. Association between shift work and the risk of death from biliary tract cancer in Japanese men. BMC Cancer 2015;15:757.
180. Devore EE, Massa J, Papantoniou K, et al. Rotating night shift work, sleep, and colorectal adenoma in women. Int J Colorectal Dis 2017;32:1013-8.
181. Papantoniou K, Devore EE, Massa J, et al. Rotating night shift work and colorectal cancer risk in the nurses’ health studies. Int J Cancer 2018;143:2709-17.
182. Nagata C, Tamura T, Wada K, et al. Sleep duration, nightshift work, and the timing of meals and urinary levels of 8-isoprostane and 6-sulfatoxymelatonin in Japanese women. Chronobiol Int 2017;34:1187-96.
183. Shan Z, Li Y, Zong G, et al. Rotating night shift work and adherence to unhealthy lifestyle in predicting risk of type 2 diabetes: results from two large US cohorts of female nurses. BMJ 2018;363:k4641.
184. Katsagoni CN, Georgoulis M, Papatheodoridis GV, Panagiotakos DB, Kontogianni MD. Effects of lifestyle interventions on clinical characteristics of patients with non-alcoholic fatty liver disease: a meta-analysis. Metabolism 2017;68:119-32.
185. Zelber-Sagi S, Grinshpan LS, Ivancovsky-Wajcman D, Goldenshluger A, Gepner Y. One size does not fit all; practical, personal tailoring of the diet to NAFLD patients. Liver Int 2022;42:1731-50.
186. Lowden A, Moreno C, Holmbäck U, Lennernäs M, Tucker P. Eating and shift work - effects on habits, metabolism and performance. Scand J Work Environ Health 2010;36:150-62.
187. Mirick DK, Bhatti P, Chen C, Nordt F, Stanczyk FZ, Davis S. Night shift work and levels of 6-sulfatoxymelatonin and cortisol in men. Cancer Epidemiol Biomarkers Prev 2013;22:1079-87.
188. Bondy SC, Campbell A. Mechanisms underlying tumor suppressive properties of melatonin. Int J Mol Sci 2018;19:2205.
189. Li Y, Li S, Zhou Y, et al. Melatonin for the prevention and treatment of cancer. Oncotarget 2017;8:39896-921.
190. El-Magd MA, Mohamed Y, El-Shetry ES, et al. Melatonin maximizes the therapeutic potential of non-preconditioned MSCs in a DEN-induced rat model of HCC. Biomed Pharmacother 2019;114:108732.
191. Moreira AJ, Ordoñez R, Cerski CT, et al. Melatonin activates endoplasmic reticulum stress and apoptosis in rats with diethylnitrosamine-induced hepatocarcinogenesis. PLoS ONE 2015;10:e0144517.
192. Asher G, Schibler U. Crosstalk between components of circadian and metabolic cycles in mammals. Cell Metab 2011;13:125-37.
194. Toledo M, Batista-Gonzalez A, Merheb E, et al. Autophagy regulates the liver clock and glucose metabolism by degrading CRY1. Cell Metab 2018;28:268-281.e4.
