REFERENCES
1. Asrani SK, Devarbhavi H, Eaton J, Kamath PS. Burden of liver diseases in the world. J Hepatol 2019;70:151-71.
2. Abenavoli L, Procopio AC, Medić-Stojanoska M, Luzza F. Non-alcoholic fatty liver disease and primary care physicians. Minerva Gastroenterol Dietol 2020;66:4-5.
3. Abenavoli L, Milanović M, Milić N, Luzza F, Giuffrè AM. Olive oil antioxidants and non-alcoholic fatty liver disease. Expert Rev Gastroenterol Hepatol 2019;13:739-49.
4. Rinella M, Charlton M. The globalization of nonalcoholic fatty liver disease: Prevalence and impact on world health. Hepatology 2016;64:19-22.
5. Abenavoli L, Peta V, Milic N. Lifestyle changes associated with a new antioxidant formulation in non-alcoholic fatty liver disease: a case series. Ann Hepatol 2015;14:121-6.
6. Michel M, Schattenberg JM. Effectiveness of lifestyle interventions in NAFLD (nonalcoholic fatty liver disease) - how are clinical trials affected? Expert Opin Investig Drugs 2020;29:93-7.
7. Lonardo A, Mantovani A, Lugari S, Targher G. NAFLD in some common endocrine diseases: prevalence, pathophysiology, and principles of diagnosis and management. Int J Mol Sci 2019;20:2841.
8. Gelli C, Tarocchi M, Abenavoli L, Di Renzo L, Galli A, et al. Effect of a counseling-supported treatment with the Mediterranean diet and physical activity on the severity of the non-alcoholic fatty liver disease. World J Gastroenterol 2017;23:3150-62.
9. Abenavoli L, Milanovic M, Procopio AC, Spampinato G, Maruca G, et al. Ancient wheats: beneficial effects on insulin resistance. Minerva Med 2020. [Online ahead of print]
10. Brunner KT, Henneberg CJ, Wilechansky RM, Long MT. Nonalcoholic Fatty Liver Disease and Obesity Treatment. Curr Obes Rep 2019;8:220-8.
11. Hamurcu Varol P, Kaya E, Alphan E, Yilmaz Y. Role of intensive dietary and lifestyle interventions in the treatment of lean nonalcoholic fatty liver disease patients. Eur J Gastroenterol Hepatol 2020;32:1352-7.
12. Cai J, Zhang XJ, Li H. Progress and challenges in the prevention and control of nonalcoholic fatty liver disease. Med Res Rev 2019;39:328-48.
13. Abenavoli L, Di Renzo L, Boccuto L, Alwardat N, Gratteri S, et al. Health benefits of Mediterranean diet in nonalcoholic fatty liver disease. Expert Rev Gastroenterol Hepatol 2018;12:873-81.
14. Abenavoli L, Boccuto L, Federico A, Dallio M, Loguercio C, et al. Diet and non-alcoholic fatty liver disease: the mediterranean way. Int J Environ Res Public Health 2019;16:3011.
15. Abenavoli L, Milic N, Luzza F, Boccuto L, De Lorenzo A. Polyphenols Treatment in Patients with Nonalcoholic Fatty Liver Disease. J Transl Int Med 2017;5:144-7.
16. Abenavoli L, Milic N, Di Renzo L, Preveden T, Medić-Stojanoska M, et al. Metabolic aspects of adult patients with nonalcoholic fatty liver disease. World J Gastroenterol 2016;22:7006-16.
17. Di Renzo L, Cioccoloni G, Bernardini S, Abenavoli L, Aiello V, et al. A hazelnut-enriched diet modulates oxidative stress and inflammation gene expression without weight gain. Oxid Med Cell Longev 2019;2019:4683723.
18. Araújo AR, Rosso N, Bedogni G, Tiribelli C, Bellentani S. Global epidemiology of non-alcoholic fatty liver disease/non-alcoholic steatohepatitis: what we need in the future. Liver Int 2018;38 Suppl 1:47-51.
19. Luk JM, Wang X, Liu P, Wong KF, Chan KL, et al. Traditional Chinese herbal medicines for treatment of liver fibrosis and cancer: from laboratory discovery to clinical evaluation. Liver Int 2007;27:879-90.
20. Philips CA, Augustine P, Rajesh S, Y PK, Madhu D. Complementary and alternative medicine-related drug-induced liver injury in Asia. J Clin Transl Hepatol 2019;7:263-74.
21. Richmond JA, Bailey DE, Patel K, Jezsik JA, Muir A, et al. The use of complementary and alternative medicine by patients with chronic hepatitis C. Complement Ther Clin Pract 2010;16:124-31.
22. Henson JB, Brown CL, Chow SC, Muir AJ. Complementary and alternative medicine use in United States adults with liver disease. J Clin Gastroenterol 2017;51:564-70.
24. Costa J, Lunet N, Santos C, Santos J, Vaz-Carneiro A. Caffeine exposure and the risk of Parkinson’s disease: a systematic review and meta-analysis of observational studies. J Alzheimers Dis 2010;20 Suppl 1:S221-38.
25. Crippa A, Discacciati A, Larsson SC, Wolk A, Orsini N. Coffee consumption and mortality from all causes, cardiovascular disease, and cancer: a dose-response meta-analysis. Am J Epidemiol 2014;180:763-75.
26. Nordestgaard AT, Stender S, Nordestgaard BG, Tybjaerg-Hansen A. Coffee intake protects against symptomatic gallstone disease in the general population: a Mendelian randomization study. J Intern Med 2020;287:42-53.
27. Lopez-Garcia E, van Dam RM, Li TY, Rodriguez-Artalejo F, Hu FB. The relationship of coffee consumption with mortality. Ann Intern Med 2008;148:904-14.
28. Freedman ND, Park Y, Abnet CC, Hollenbeck AR, Sinha R. Association of coffee drinking with total and cause-specific mortality. N Engl J Med 2012;366:1891-904.
29. Nehlig A, Daval J, Debry G. Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects. Brain Res Rev 1992;17:139-70.
30. Shim SG, Jun DW, Kim EK, Saeed WK, Lee KN, et al. Caffeine attenuates liver fibrosis via defective adhesion of hepatic stellate cells in cirrhotic model. J Gastroenterol Hepatol 2013;28:1877-84.
31. Gressner OA, Lahme B, Rehbein K, Siluschek M, Weiskirchen R, et al. Pharmacological application of caffeine inhibits TGF-beta-stimulated connective tissue growth factor expression in hepatocytes via PPARgamma and SMAD2/3-dependent pathways. J Hepatol 2008;49:758-67.
32. Quan HY, Kim DY, Chung SH. Caffeine attenuates lipid accumulation via activation of AMP-activated protein kinase signaling pathway in HepG2 cells. BMB Rep 2013;46:207-12.
33. Helal MG, Ayoub SE, Elkashefand WF, Ibrahim TM. Caffeine affects HFD-induced hepatic steatosis by multifactorial intervention. Hum Exp Toxicol 2018;37:983-90.
34. Perumpail BJ, Li AA, Iqbal U, Sallam S, Shah ND, et al. Potential therapeutic benefits of Herbs and supplements in patients with NAFLD. Diseases 2018;6:80.
35. Watanabe S, Takahashi T, Ogawa H, Uehara H, Tsunematsu T, et al. Daily coffee intake inhibits pancreatic beta cell damage and nonalcoholic steatohepatitis in a mouse model of spontaneous metabolic syndrome, tsumura-suzuki obese diabetic mice. Metab Syndr Relat Disord 2017;15:170-7.
36. Di Renzo L, Marsella LT, Carraro A, Valente R, Gualtieri P, et al. Changes in LDL oxidative status and oxidative and inflammatory gene expression after red wine intake in healthy people: a randomized trial. Mediators Inflamm 2015;2015:317348.
37. Colica C, Di Renzo L, Trombetta D, Smeriglio A, Bernardini S, et al. Antioxidant effects of a hydroxytyrosol-based pharmaceutical formulation on body composition, metabolic state, and gene expression: a randomized double-blinded, placebo-controlled crossover trial. Oxid Med Cell Longev 2017;2017:2473495.
38. Meng S, Cao J, Feng Q, Peng J, Hu Y. Roles of chlorogenic acid on regulating glucose and lipids metabolism: a review. Evid Based Complement Alternat Med 2013;2013:801457.
39. Zduńska K, Dana A, Kolodziejczak A, Rotsztejn H. Antioxidant properties of ferulic acid and its possible application. Skin Pharmacol Physiol 2018;31:332-6.
40. Sarwar T, Zafaryab M, Husain MA, Ishqi HM, Rehman SU, et al. Redox cycling of endogenous copper by ferulic acid leads to cellular DNA breakage and consequent cell death: A putative cancer chemotherapy mechanism. Toxicol Appl Pharmacol 2015;289:251-61.
41. Hosseinabadi S, Rafraf M, Asghari S, Asghari-Jafarabadi M, Vojouhi S. Effect of green coffee extract supplementation on serum adiponectin concentration and lipid profile in patients with non-alcoholic fatty liver disease: a randomized, controlled trial. Complement Ther Med 2020;49:102290.
42. Graeter T, Niedermayer PC, Mason RA, Oeztuerk S, Haenle MM, et al; EMIL-Study group. Coffee consumption and NAFLD: a community based study on 1223 subjects. BMC Res Notes 2015;8:640.
43. Bambha K, Wilson LA, Unalp A, Loomba R, Neuschwander-Tetri BA, et al; Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). Coffee consumption in NAFLD patients with lower insulin resistance is associated with lower risk of severe fibrosis. Liver Int 2014;34:1250-8.
44. Anty R, Marjoux S, Iannelli A, Patouraux S, Schneck AS, et al. Regular coffee but not espresso drinking is protective against fibrosis in a cohort mainly composed of morbidly obese European women with NAFLD undergoing bariatric surgery. J Hepatol 2012;57:1090-6.
45. Zelber-Sagi S, Salomone F, Webb M, Lotan R, Yeshua H, et al. Coffee consumption and nonalcoholic fatty liver onset: a prospective study in the general population. Transl Res 2015;165:428-36.
46. Hodge A, Lim S, Goh E, Wong O, Marsh P, et al. Coffee intake is associated with a lower liver stiffness in patients with non-alcoholic fatty liver disease, Hepatitis C, and Hepatitis B. Nutrients 2017;9:56.
47. Alferink LJM, Fittipaldi J, Kiefte-de Jong JC, Taimr P, Hansen BE, et al. Coffee and herbal tea consumption is associated with lower liver stiffness in the general population: the Rotterdam study. J Hepatol 2017;67:339-48.