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From: Intraarterial and intravenous contrast enhanced CT and MR imaging of multi-step hepatocarcinogenesis defining the early stage of hepatocellular carcinoma development

Intraarterial and intravenous contrast enhanced CT and MR imaging of multi-step hepatocarcinogenesis defining the early stage of hepatocellular carcinoma development

Figure 1. Schematic diagram of multistep hepatocarcinogenesis. Two types of human hepatocarcinogenesis are currently considered, one is multistep- and the other is de novo-hepatocarcinogenesis. In multistep hepatocarcinogenesis, the nodular grade of malignancy changes from dysplastic nodule to advanced HCC stepwisely, and nodular vascularity also gradually change from hypovascular to hypervascular. HCC: hepatocellular carcinoma

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