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Figure 3. Major clinical applications and shared mechanisms of bioactive therapy based on adipose-derived products. Although adipose-derived therapeutics differ in form - including ADSCs, SVF, exosomes, and dECM - they all contribute to tissue repair through common mechanisms such as anti-inflammation, angiogenesis, anti-fibrosis, promotion of cell migration, and microenvironment remodeling, and are further applied in chronic wound repair, scar and fibrosis intervention, skin regeneration and rejuvenation, repair of radiation-induced injury, breast reconstruction, and biomaterial-assisted regenerative therapy. Created in BioRender. Lu, R. (2026) https://BioRender.com/mmdhdf7. ADSCs: Adipose-derived stem cells; SVF: stromal vascular fraction; EVs: extracellular vesicles; dECM: decellularized extracellular matrix.