fig1

Role of mechanical forces and skin tension in scar pathophysiology

Figure 1. Cellular signaling pathways in mechanotransduction in scar formation. Adapted from Berry et al., Frontiers in Surgery, 2023[49], licensed under CC BY 4.0. FAK: Focal adhesion kinase; MAPK: mitogen-activated protein kinase; ROCK: Rho-associated coiled-coil containing protein kinase; YAP: Yes-associated protein; TAZ: transcriptional coactivator with PDZ-binding motif; TGF-β: transforming growth factor-beta; Smad: suppressor of mothers against decapentaplegic homolog.

Plastic and Aesthetic Research
ISSN 2349-6150 (Online)   2347-9264 (Print)

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